Zytiga and International normalised ratio increased - a phase IV clinical study of FDA data

Summary:

International normalised ratio increased is reported as a side effect among people who take Zytiga (abiraterone acetate), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Xtandi, and have Prostate cancer.

The phase IV clinical study analyzes which people have International normalised ratio increased when taking Zytiga. It is created by eHealthMe based on reports of 29,870 people who have side effects when taking Zytiga from the FDA, and is updated regularly.

What is Zytiga?

Zytiga has active ingredients of abiraterone acetate. It is often used in prostate cancer metastatic. eHealthMe is studying from 29,928 Zytiga users. Check the latest studies of Zytiga.

What is International normalised ratio increased?

International normalised ratio increased is found to be associated with 1,340 drugs and 1,726 conditions by eHealthMe. Check the latest studies of International normalised ratio increased.

On Jul, 10, 2026

29,870 people reported to have side effects when taking Zytiga.
Among them, 24 people (0.08%) have International normalised ratio increased.

Could Zytiga cause International normalised ratio increased?

Among these 24 people:

How long have people been on Zytiga when they have International normalised ratio increased? *

What is the gender of people who have International normalised ratio increased when taking Zytiga? *

female: 0.0 %
male: 100 %

What is the age of people who have International normalised ratio increased when taking Zytiga? *

What are other drugs people take besides Zytiga? *

What are other side effects people have besides International normalised ratio increased? *

Weakness: 8 people, 33.33%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 4 people, 16.67%
Haematuria (presence of blood in urine): 3 people, 12.50%
Bleeding Disorders: 3 people, 12.50%
Fatigue (feeling of tiredness): 3 people, 12.50%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 12.50%
Peripheral Swelling: 3 people, 12.50%
Fever: 3 people, 12.50%
Haemorrhagic Anaemia (anaemia due to excessive bleeding): 2 people, 8.33%
Arteriovenous Malformation: 2 people, 8.33%

What are the existing conditions these people have? *

Prostate Cancer: 9 people, 37.50%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 16.67%
Hypertensive Heart Disease: 2 people, 8.33%
High Blood Cholesterol: 2 people, 8.33%
Urinary Tract Infection: 1 person, 4.17%
Thyroid Diseases: 1 person, 4.17%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 4.17%
Pulmonary Thrombosis (scarring in the lungs): 1 person, 4.17%
Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 4.17%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Zytiga and have International normalised ratio increased?

- Check whether International normalised ratio increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zytiga:

Zytiga (29,928 reports)

International normalised ratio increased treatments and more:

International normalised ratio increased (40,071 reports)

How severe was International normalised ratio increased and when was it recovered:

International normalised ratio increased in Zytiga

Expand to all the drugs that have ingredients of abiraterone acetate:

International normalised ratio increased and drugs with ingredients of abiraterone acetate (20 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zytiga:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with International normalised ratio increased:

International normalised ratio increased (1,340 drugs)

Browse all the conditions that are associated with International normalised ratio increased:

International normalised ratio increased (1,726 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on abiraterone acetate (the active ingredients of Zytiga) and Zytiga (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.