Zyvox and Mental status changes - a phase IV clinical study of FDA data

Summary:

Mental status changes is reported as a side effect among people who take Zyvox (linezolid), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lorazepam, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Mental status changes when taking Zyvox. It is created by eHealthMe based on reports of 9,233 people who have side effects when taking Zyvox from the FDA, and is updated regularly.

What is Zyvox?

Zyvox has active ingredients of linezolid. It is often used in mrsa infection. eHealthMe is studying from 9,399 Zyvox users. Check the latest studies of Zyvox.

What is Mental status changes?

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation) is found to be associated with 1,499 drugs and 1,759 conditions by eHealthMe. Check the latest studies of Mental status changes.

On Jul, 08, 2026

9,233 people reported to have side effects when taking Zyvox.
Among them, 56 people (0.61%) have Mental status changes.

Could Zyvox cause Mental status changes?

Among these 56 people:

How long have people been on Zyvox when they have Mental status changes? *

What is the gender of people who have Mental status changes when taking Zyvox? *

female: 65.45 %
male: 34.55 %

What is the age of people who have Mental status changes when taking Zyvox? *

What are other drugs people take besides Zyvox? *

What are other side effects people have besides Mental status changes? *

Thrombocytopenia (decrease of platelets in blood): 25 people, 44.64%
Pneumonia: 23 people, 41.07%
Anaemia (lack of blood): 22 people, 39.29%
Chronic Renal Failure (kidney failure): 22 people, 39.29%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 21 people, 37.50%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 21 people, 37.50%
Back Pain: 21 people, 37.50%
Bone Disorder: 20 people, 35.71%
Spinal Osteoarthritis (joint cartilage loss in spine): 20 people, 35.71%
Confusional State: 20 people, 35.71%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 10.71%
Pain: 4 people, 7.14%
Depression: 3 people, 5.36%
Staphylococcal Infection (an infection with staphylococcus bacteria): 2 people, 3.57%
Anaemia (lack of blood): 2 people, 3.57%
Skin Infection: 2 people, 3.57%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 3.57%
Gastric Ulcer (stomach ulcer): 2 people, 3.57%
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 2 people, 3.57%
Excoriation (to tear or wear off the skin of): 2 people, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Zyvox and have Mental status changes?

- Check whether Mental status changes is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyvox:

Zyvox (9,399 reports)

Browse all side effects of Zyvox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mental status changes:

Mental status changes (1,499 drugs)

Browse all the conditions that are associated with Mental status changes:

Mental status changes (1,759 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on linezolid (the active ingredients of Zyvox) and Zyvox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.