Constipation in Codeine - how severe and when it was recovered? (a real world drug study)

Summary:

We study how severe was Constipation, when it was recovered, drug effectiveness, race, and more among people who take Codeine (codeine sulfate). This phase IV clinical study is created by eHealthMe based on reports submitted to eHealthMe, and is updated regularly.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,341 Codeine users. Check the latest studies of Codeine.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,579 conditions by eHealthMe. Check the latest studies of Constipation.



On Jan, 03, 2026

8 people who have Constipation while taking Codeine were studied.

Could Codeine cause Constipation?

Severity of Constipation *:

  • least: 0.0 %
  • moderate: 20 %
  • severe: 60 %
  • most severe: 20 %

When people recovered from Constipation *:

  • while on drug: 0.0 %
  • after off the drug: 33.33 %
  • not yet: 66.67 %

Effectiveness of Codeine *:

  • not at all: 0.0 %
  • somewhat: 50 %
  • moderate: 25 %
  • high: 25 %
  • very high: 0.0 %

Race of the people *:

  • African American, Non-Hispanic: 0.0 %
  • American Indian/Alaska Native: 0.0 %
  • Asian: 0.0 %
  • Hispanic: 0.0 %
  • Native Hawaiians/Pacific Islanders: 0.0 %
  • Two or more races: 0.0 %
  • White, Non-Hispanic: 100 %

Time on Codeine *:

  • < 1 month: 20 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 40 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 20 %

Gender of people when taking Codeine *:

  • female: 100 %
  • male: 0.0 %

Age of people when taking Codeine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 25.0 %
  • 30-39: 37.5 %
  • 40-49: 12.5 %
  • 50-59: 12.5 %
  • 60+: 12.5 %

Conditions people have *:

  1. Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 1 person, 12.50%
  2. Inflammation: 1 person, 12.50%
  3. Bladder Spasm: 1 person, 12.50%
  4. Cough Aggravated: 1 person, 12.50%
  5. Depressed Mood: 1 person, 12.50%
  6. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 12.50%
  7. Hair Loss: 1 person, 12.50%
  8. Incontinence (lack of moderation or self-control): 1 person, 12.50%
  9. Irritable Bowel Syndrome: 1 person, 12.50%
  10. Spasticity (weakness and loss of muscle control due to nerve damage in brain): 1 person, 12.50%

Other drugs people take besides Codeine *:

  1. Paracetamol: 3 people, 37.50%
  2. Baclofen: 2 people, 25.00%
  3. Naproxen: 2 people, 25.00%
  4. Gabapentin: 2 people, 25.00%
  5. Vitamin D: 1 person, 12.50%
  6. Lyrica: 1 person, 12.50%
  7. B12: 1 person, 12.50%
  8. Diclofenac Sodium: 1 person, 12.50%
  9. Ferrous Fumarate: 1 person, 12.50%
  10. Folate: 1 person, 12.50%

Other side effects people have besides Constipation *:

  1. Nausea (feeling of having an urge to vomit): 3 people, 37.50%
  2. Headache (pain in head): 2 people, 25.00%
  3. Diarrhea: 2 people, 25.00%
  4. Urinary Tract Infection: 1 person, 12.50%
  5. Emotional Distress: 1 person, 12.50%
  6. High Blood Cholesterol: 1 person, 12.50%
  7. Heat Intolerance (feeling of being overheated): 1 person, 12.50%
  8. Gastroparesis (delayed emptying of food from the stomach): 1 person, 12.50%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 12.50%
  10. Gallbladder Disease: 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Codeine and have Constipation?

Check whether Constipation is associated with a drug or a condition

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

How the study uses the data?

The study is based on codeine sulfate (the active ingredients of Codeine). Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: