Sciatica in Repatha - how severe and when it was recovered? (a real world drug study)

Summary:

We study how severe was Sciatica, when it was recovered, drug effectiveness, race, and more among people who take Repatha (evolocumab). This phase IV clinical study is created by eHealthMe based on reports submitted to eHealthMe, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,254 Repatha users. Check the latest studies of Repatha.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,143 drugs and 1,433 conditions by eHealthMe. Check the latest studies of Sciatica.



On Jun, 09, 2026

4 people who have Sciatica while taking Repatha were studied.

Could Repatha cause Sciatica?

Severity of Sciatica *:

  • least: 0.0 %
  • moderate: 25 %
  • severe: 50 %
  • most severe: 25 %

When people recovered from Sciatica *:

  • while on drug: 33.33 %
  • after off the drug: 0.0 %
  • not yet: 66.67 %

Effectiveness of Repatha *:

  • not at all: 0.0 %
  • somewhat: 0.0 %
  • moderate: 0.0 %
  • high: 50 %
  • very high: 50 %

Race of the people *:

  • African American, Non-Hispanic: 0.0 %
  • American Indian/Alaska Native: 0.0 %
  • Asian: 25 %
  • Hispanic: 0.0 %
  • Native Hawaiians/Pacific Islanders: 0.0 %
  • Two or more races: 25 %
  • White, Non-Hispanic: 50 %

Time on Repatha *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people when taking Repatha *:

  • female: 50 %
  • male: 50 %

Age of people when taking Repatha *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 50 %
  • 60+: 50 %

Conditions people have *:

  1. Immune Response: 2 people, 50.00%
  2. High Blood Pressure: 2 people, 50.00%
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 25.00%
  4. Muscle Cramps (painful sensations caused by muscle contraction): 1 person, 25.00%
  5. Leukemia (a type of cancer of the blood or bone marrow): 1 person, 25.00%
  6. Insulin-Requiring Type Ii Diabetes Mellitus: 1 person, 25.00%
  7. Hypokalemia (low potassium): 1 person, 25.00%
  8. Herpes Zoster: 1 person, 25.00%
  9. Esophageal Cancer: 1 person, 25.00%
  10. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 25.00%

Other drugs people take besides Repatha *:

  1. Zinc Sulfate: 1 person, 25.00%
  2. Magnesium Glycinate: 1 person, 25.00%
  3. Advil: 1 person, 25.00%
  4. Alendronic Acid: 1 person, 25.00%
  5. Arg: 1 person, 25.00%
  6. Atenolol: 1 person, 25.00%
  7. Bayer Low Dose Aspirin (81mg Aspirin): 1 person, 25.00%
  8. Celexa: 1 person, 25.00%
  9. Gabapentin: 1 person, 25.00%
  10. Glucosamine: 1 person, 25.00%

Other side effects people have besides Sciatica *:

  1. Peripheral Neuropathy (damage to nerves of the peripheral nervous system): 1 person, 25.00%
  2. Herpes Zoster: 1 person, 25.00%
  3. Esophageal Cancer: 1 person, 25.00%
  4. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 25.00%
  5. Enlarged Prostate: 1 person, 25.00%
  6. Dizziness: 1 person, 25.00%
  7. Diplopia (double vision): 1 person, 25.00%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 25.00%
  9. Anticipatory Anxiety (anxiety that we experience in anticipation of exposure to our frightening triggers): 1 person, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Repatha and have Sciatica?

Check whether Sciatica is associated with a drug or a condition

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

How the study uses the data?

The study is based on evolocumab (the active ingredients of Repatha). Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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