Constipation in Sinemet - how severe and when it was recovered? (a real world drug study)

Summary:

We study how severe was Constipation, when it was recovered, drug effectiveness, race, and more among people who take Sinemet (carbidopa; levodopa). This phase IV clinical study is created by eHealthMe based on reports submitted to eHealthMe, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,618 conditions by eHealthMe. Check the latest studies of Constipation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jun, 12, 2026

18 people who have Constipation while taking Sinemet were studied.

Severity of Constipation *:

least: 6.25 %
moderate: 25.0 %
severe: 56.25 %
most severe: 12.5 %

When people recovered from Constipation *:

while on drug: 0.0 %
after off the drug: 0.0 %
not yet: 100 %

Effectiveness of Sinemet *:

not at all: 0.0 %
somewhat: 23.08 %
moderate: 30.77 %
high: 23.08 %
very high: 23.08 %

Race of the people *:

African American, Non-Hispanic: 0.0 %
American Indian/Alaska Native: 0.0 %
Asian: 6.67 %
Hispanic: 0.0 %
Native Hawaiians/Pacific Islanders: 0.0 %
Two or more races: 0.0 %
White, Non-Hispanic: 93.33 %

Time on Sinemet *:

Gender of people when taking Sinemet *:

female: 16.67 %
male: 83.33 %

Age of people when taking Sinemet *:

Conditions people have *:

High Blood Cholesterol: 2 people, 11.11%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 2 people, 11.11%
Urinary Tract Infection - Chronic Or Recurrent: 1 person, 5.56%
Stress And Anxiety: 1 person, 5.56%
Stable Angina (a constant chest pain): 1 person, 5.56%
Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 1 person, 5.56%
Pain: 1 person, 5.56%
Insomnia (sleeplessness): 1 person, 5.56%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.56%
Growth Hormone Deficiency: 1 person, 5.56%

Other drugs people take besides Sinemet *:

Clonazepam: 3 people, 16.67%
Amantadine Hydrochloride: 2 people, 11.11%
Selegiline Hydrochloride: 2 people, 11.11%
Crestor: 1 person, 5.56%
Genotropin: 1 person, 5.56%
Furosemide: 1 person, 5.56%
Folic Acid: 1 person, 5.56%
Flexeril: 1 person, 5.56%
Estrace: 1 person, 5.56%
Diazepam: 1 person, 5.56%

Other side effects people have besides Constipation *:

Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 11.11%
Weakness: 1 person, 5.56%
Varicose Vein (veins that have become enlarged and tortuous): 1 person, 5.56%
Urinary Tract Infection: 1 person, 5.56%
Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below): 1 person, 5.56%
Sedation: 1 person, 5.56%
Rashes (redness): 1 person, 5.56%
Insomnia (sleeplessness): 1 person, 5.56%
Gastrointestinal Discomfort: 1 person, 5.56%
Faecaloma (hard mass of fecal matter): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Sinemet and have Constipation?

Check whether Constipation is associated with a drug or a condition

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Constipation in Sinemet

How the study uses the data?

The study is based on carbidopa; levodopa (the active ingredients of Sinemet). Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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