Adderall xr 25 vs. Fluoxetine hydrochloride: side effect and effectiveness comparison (a real world drug study)

Summary:

We compare the side effects and drug effectiveness of Adderall xr 25 and Fluoxetine hydrochloride. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 258,648 people who take Adderall xr 25 and Fluoxetine hydrochloride, and is updated regularly.

What is Adderall xr 25?

Adderall xr 25 has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 345 Adderall xr 25 users. Check the latest studies of Adderall xr 25.

What is Fluoxetine hydrochloride?

Fluoxetine hydrochloride has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 13,381 Fluoxetine hydrochloride users. Check the latest studies of Fluoxetine hydrochloride.



On Jul, 05, 2026

258,648 people who take Adderall xr 25 and Fluoxetine hydrochloride are studied.

Adderall xr 25 vs Fluoxetine hydrochloride drug comparison reports.

Drugs being compared in this study:

  • Adderall Xr 25 (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate)
  • Fluoxetine Hydrochloride (fluoxetine hydrochloride)

Most common side effects of the drugs, overall:

Click here to view

Most common side effects of the drugs, in long term (1+ years) use:

Click here to view

Drug effectiveness:

Adderall Xr 25:

  • not at all: 1.25 %
  • somewhat: 11.61 %
  • moderate: 31.9 %
  • high: 39.67 %
  • very high: 15.57 %

Fluoxetine Hydrochloride:

  • not at all: 3.93 %
  • somewhat: 21.17 %
  • moderate: 35.68 %
  • high: 30.43 %
  • very high: 8.79 %

Want to compare Adderall xr 25 with Fluoxetine hydrochloride?

- Personalize this study to your gender and age (0-99+)

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.



Related studies

Alternative drugs to, pros and cons of:

Browse all side effects of Adderall xr 25:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fluoxetine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study is based on amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate and fluoxetine hydrochloride (the active ingredients of Adderall xr 25 and Fluoxetine hydrochloride, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: