Advil vs. Mepergan: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Advil and Mepergan. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 354,584 people who take Advil and Mepergan, and is updated regularly.
What is Advil?
Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,534 Advil users. Check the latest studies of Advil.
What is Mepergan?
Mepergan has active ingredients of meperidine hydrochloride; promethazine hydrochloride. It is often used in pain. eHealthMe is studying from 211 Mepergan users. Check the latest studies of Mepergan.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
354,584 people who take Advil and Mepergan are studied.

Drugs being compared in this study:
- Advil (ibuprofen)
- Mepergan (meperidine hydrochloride; promethazine hydrochloride)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Advil:
- not at all: 2.89 %
- somewhat: 24.59 %
- moderate: 38.43 %
- high: 26.2 %
- very high: 7.89 %
Mepergan:
- not at all: 0 %
- somewhat: 33.33 %
- moderate: 66.67 %
- high: 0 %
- very high: 0 %
Want to compare Advil with Mepergan?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Related studies
Alternative drugs to, pros and cons of:
Browse all side effects of Advil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Mepergan:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on ibuprofen and meperidine hydrochloride; promethazine hydrochloride (the active ingredients of Advil and Mepergan, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Proscar and Lipoic Acid drug interactions for men aged 60+ - now
- Aspirin and Cardiac Arrest for Girls aged 10-19 - 6 seconds ago
- Lidoderm vs. Fentanyl-75, side effect and effectiveness comparison - 8 seconds ago
- Gravol and Alvesco drug interactions for girls aged 10-19 - 10 seconds ago
- Itching and drugs of ingredients of prednisone - 11 seconds ago
- Could Aspirin cause Mucosal Inflammation? - 12 seconds ago
- Drug Administration Error and drugs of ingredients of gentamicin sulfate - 13 seconds ago
- Could Clopidogrel Bisulfate cause Myocardial Ischaemia? - 15 seconds ago
- Drug interactions of Selenium and Magnesium Oxide - 16 seconds ago
- Remodulin and Pain for Girls aged 10-19 - 18 seconds ago