Botox vs. Valproate sodium: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Botox and Valproate sodium. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 109,999 people who take Botox and Valproate sodium, and is updated regularly.
What is Botox?
Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.
What is Valproate sodium?
Valproate sodium has active ingredients of valproate sodium. It is often used in epilepsy. eHealthMe is studying from 24,044 Valproate sodium users. Check the latest studies of Valproate sodium.
109,999 people who take Botox and Valproate sodium are studied.

Drugs being compared in this study:
- Valproate Sodium (valproate sodium)
- Botox (botulinum toxin type a)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Botox:
- not at all: 7.4 %
- somewhat: 13.83 %
- moderate: 25.72 %
- high: 30.23 %
- very high: 22.83 %
Valproate Sodium:
- not at all: 3.8200000000000003 %
- somewhat: 12.17 %
- moderate: 28.64 %
- high: 39.62 %
- very high: 15.75 %
Want to compare Botox with Valproate sodium?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2017 Jan .
- Bansal S, Gupta SK, "Sodium Valproate induced priapism in an adult with bipolar affective disorder", Indian journal of pharmacology, 2013 Jan .
- Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2017 Jan .
- Bansal S, Gupta SK, "Sodium Valproate induced priapism in an adult with bipolar affective disorder", Indian journal of pharmacology, 2013 Jan .
Related studies
Alternative drugs to, pros and cons of:
- Botox (69,987 reports)
- Valproate sodium (23,476 reports)
Browse all side effects of Botox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Valproate sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on botulinum toxin type a and valproate sodium (the active ingredients of Botox and Valproate sodium, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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