Centrax vs. Risperdal: side effect and effectiveness comparison (a real world drug study)

Summary:

We compare the side effects and drug effectiveness of Centrax and Risperdal. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 187,506 people who take Centrax and Risperdal, and is updated regularly.

What is Centrax?

Centrax has active ingredients of prazepam. It is often used in stress and anxiety. eHealthMe is studying from 35 Centrax users. Check the latest studies of Centrax.

What is Risperdal?

Risperdal has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 127,728 Risperdal users. Check the latest studies of Risperdal.



On Jun, 23, 2026

187,506 people who take Centrax and Risperdal are studied.

Centrax vs Risperdal drug comparison reports.

Drugs being compared in this study:

  • Centrax (prazepam)
  • Risperdal (risperidone)

Most common side effects of the drugs, overall:

Centrax:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Coma (state of unconsciousness lasting more than six hours)
  3. Fall
  4. Hypotension (abnormally low blood pressure)
  5. Poisoning Deliberate
  6. Suicide Attempt
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Drug Abuse
  9. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  10. Nausea (feeling of having an urge to vomit)

Risperdal:

  1. Gynaecomastia (enlargement of the gland tissue of the male breast)
  2. Abnormal Weight Gain
  3. Injury
  4. Emotional Disorder
  5. Weight Increased
  6. Drug Ineffective
  7. Hyperprolactinaemia (abnormally high levels of prolactin in the blood)
  8. Galactorrhoea (secretion of breast milk in men)
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Emotional Distress

Most common side effects of the drugs, in long term (1+ years) use:

Centrax:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Depression
  3. Abdominal Pain Upper
  4. Pneumonia
  5. Colitis (inflammation of colon)
  6. Pain In Extremity
  7. Pain
  8. Orchitis (inflammation of the testes)
  9. Oesophageal Candidiasis (fungal infection of oesophagus)
  10. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

Risperdal:

  1. Gynaecomastia (enlargement of the gland tissue of the male breast)
  2. Emotional Disorder
  3. Abnormal Weight Gain
  4. Weight Increased
  5. Emotional Distress
  6. Hyperprolactinaemia (abnormally high levels of prolactin in the blood)
  7. Obesity (having too much body fat)
  8. Galactorrhoea (secretion of breast milk in men)
  9. Extrapyramidal Disorder (involuntary muscle spasms in the face and neck)
  10. Drug Ineffective

Drug effectiveness:

Centrax:

  • not at all: 6.25 %
  • somewhat: 25.0 %
  • moderate: 31.25 %
  • high: 25.0 %
  • very high: 12.5 %

Risperdal:

  • not at all: 7.68 %
  • somewhat: 24.77 %
  • moderate: 33.64 %
  • high: 25.1 %
  • very high: 8.81 %

Want to compare Centrax with Risperdal?

- Personalize this study to your gender and age (0-99+)

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.



Related publications that referenced our studies

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Alternative drugs to, pros and cons of:

Browse all side effects of Centrax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Risperdal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study is based on prazepam and risperidone (the active ingredients of Centrax and Risperdal, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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