Lotemax vs. Durezol: side effect and effectiveness comparison (a real world drug study)

Summary:

We compare the side effects and drug effectiveness of Lotemax and Durezol. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 10,550 people who take Lotemax and Durezol, and is updated regularly.

What is Lotemax?

Lotemax has active ingredients of loteprednol etabonate. It is often used in inflammation. eHealthMe is studying from 4,431 Lotemax users. Check the latest studies of Lotemax.

What is Durezol?

Durezol has active ingredients of difluprednate. It is often used in uveitis. eHealthMe is studying from 3,441 Durezol users. Check the latest studies of Durezol.



On May, 20, 2026

10,550 people who take Lotemax and Durezol are studied.

Lotemax vs Durezol drug comparison reports.

Drugs being compared in this study:

  • Durezol (difluprednate)
  • Lotemax (loteprednol etabonate)

Most common side effects of the drugs, overall:

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Most common side effects of the drugs, in long term (1+ years) use:

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Drug effectiveness:

Lotemax:

  • not at all: 8.51 %
  • somewhat: 34.04 %
  • moderate: 14.89 %
  • high: 25.53 %
  • very high: 17.02 %

Durezol:

  • not at all: 9.09 %
  • somewhat: 22.73 %
  • moderate: 9.09 %
  • high: 45.45 %
  • very high: 13.64 %

Want to compare Lotemax with Durezol?

- Personalize this study to your gender and age (0-99+)

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.



Related studies

Alternative drugs to, pros and cons of:

Browse all side effects of Lotemax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Durezol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study is based on loteprednol etabonate and difluprednate (the active ingredients of Lotemax and Durezol, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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