Lotrel vs. Propranolol hydrochloride: side effect and effectiveness comparison (a real world drug study)

Summary:

We compare the side effects and drug effectiveness of Lotrel and Propranolol hydrochloride. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 102,637 people who take Lotrel and Propranolol hydrochloride, and is updated regularly.

What is Lotrel?

Lotrel has active ingredients of amlodipine besylate; benazepril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,571 Lotrel users. Check the latest studies of Lotrel.

What is Propranolol hydrochloride?

Propranolol hydrochloride has active ingredients of propranolol hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 12,026 Propranolol hydrochloride users. Check the latest studies of Propranolol hydrochloride.



On Jul, 19, 2026

102,637 people who take Lotrel and Propranolol hydrochloride are studied.

Lotrel vs Propranolol hydrochloride drug comparison reports.

Drugs being compared in this study:

  • Lotrel (amlodipine besylate; benazepril hydrochloride)
  • Propranolol Hydrochloride (propranolol hydrochloride)

Most common side effects of the drugs, overall:

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Most common side effects of the drugs, in long term (1+ years) use:

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Drug effectiveness:

Lotrel:

  • not at all: 0.24 %
  • somewhat: 8.77 %
  • moderate: 32.23 %
  • high: 42.42 %
  • very high: 16.35 %

Propranolol Hydrochloride:

  • not at all: 2.69 %
  • somewhat: 20.7 %
  • moderate: 30.86 %
  • high: 30.63 %
  • very high: 15.12 %

Want to compare Lotrel with Propranolol hydrochloride?

- Personalize this study to your gender and age (0-99+)

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.



Related studies

Alternative drugs to, pros and cons of:

Browse all side effects of Lotrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Propranolol hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study is based on amlodipine besylate; benazepril hydrochloride and propranolol hydrochloride (the active ingredients of Lotrel and Propranolol hydrochloride, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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