Lupron depot vs. Provera: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Lupron depot and Provera. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 166,281 people who take Lupron depot and Provera, and is updated regularly.
What is Lupron depot?
Lupron depot has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 27,037 Lupron depot users. Check the latest studies of Lupron depot.
What is Provera?
Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.
166,281 people who take Lupron depot and Provera are studied.
Drugs being compared in this study:
- Provera (medroxyprogesterone acetate)
- Lupron Depot (leuprolide acetate)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Lupron Depot:
- not at all: 8.87 %
- somewhat: 19.7 %
- moderate: 25.37 %
- high: 31.03 %
- very high: 15.02 %
Provera:
- not at all: 3.81 %
- somewhat: 7.23 %
- moderate: 12.65 %
- high: 33.87 %
- very high: 42.44 %
Want to compare Lupron depot with Provera?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
- Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
Related studies
Alternative drugs to, pros and cons of:
- Lupron depot (26,735 reports)
- Provera (53,367 reports)
Browse all side effects of Lupron depot:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Provera:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on leuprolide acetate and medroxyprogesterone acetate (the active ingredients of Lupron depot and Provera, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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