Mexate vs. Oxycontin: side effect and effectiveness comparison (a real world drug study)

Summary:

We compare the side effects and drug effectiveness of Mexate and Oxycontin. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 945,250 people who take Mexate and Oxycontin, and is updated regularly.

What is Mexate?

Mexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 81 Mexate users. Check the latest studies of Mexate.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.



On Jul, 06, 2026

945,250 people who take Mexate and Oxycontin are studied.

Mexate vs Oxycontin drug comparison reports.

Drugs being compared in this study:

  • Oxycontin (oxycodone hydrochloride)
  • Mexate (methotrexate sodium)

Most common side effects of the drugs, overall:

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Most common side effects of the drugs, in long term (1+ years) use:

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Drug effectiveness:

Mexate:

  • not at all: 6.02 %
  • somewhat: 25.52 %
  • moderate: 34.59 %
  • high: 26.19 %
  • very high: 7.68 %

Oxycontin:

  • not at all: 1.56 %
  • somewhat: 16.34 %
  • moderate: 39.03 %
  • high: 29.77 %
  • very high: 13.31 %

Want to compare Mexate with Oxycontin?

- Personalize this study to your gender and age (0-99+)

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.



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Alternative drugs to, pros and cons of:

Browse all side effects of Mexate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Oxycontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study is based on methotrexate sodium and oxycodone hydrochloride (the active ingredients of Mexate and Oxycontin, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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