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Pepcid vs. Gaviscon: side effect and effectiveness comparison (a real world drug study)

Summary:

We compare the side effects and drug effectiveness of Pepcid and Gaviscon. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 153,087 people who take Pepcid and Gaviscon, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

What is Gaviscon?

Gaviscon has active ingredients of aluminum hydroxide; magnesium trisilicate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 12,355 Gaviscon users. Check the latest studies of Gaviscon.

On Jun, 01, 2026

153,087 people who take Pepcid and Gaviscon are studied.

Pepcid vs Gaviscon drug comparison reports.

Drugs being compared in this study:

  • Gaviscon (aluminum hydroxide; magnesium trisilicate)
  • Pepcid (famotidine)

Most common side effects of the drugs, overall:

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Most common side effects of the drugs, in long term (1+ years) use:

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Drug effectiveness:

Pepcid:

  • not at all: 2.36 %
  • somewhat: 20.49 %
  • moderate: 34.5 %
  • high: 30.86 %
  • very high: 11.79 %

Gaviscon:

  • not at all: 2.08 %
  • somewhat: 22.92 %
  • moderate: 42.5 %
  • high: 25.0 %
  • very high: 7.5 %

Want to compare Pepcid with Gaviscon?

- Personalize this study to your gender and age (0-99+)

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Alternative drugs to, pros and cons of:

Browse all side effects of Pepcid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gaviscon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study is based on famotidine and aluminum hydroxide; magnesium trisilicate (the active ingredients of Pepcid and Gaviscon, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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