Promethazine vs. Tussicaps: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Promethazine and Tussicaps. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 60,343 people who take Promethazine and Tussicaps, and is updated regularly.
What is Promethazine?
Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.
What is Tussicaps?
Tussicaps has active ingredients of chlorpheniramine polistirex; hydrocodone polistirex. It is often used in cough. eHealthMe is studying from 71 Tussicaps users. Check the latest studies of Tussicaps.
60,343 people who take Promethazine and Tussicaps are studied.

Drugs being compared in this study:
- Promethazine (promethazine hydrochloride)
- Tussicaps (chlorpheniramine polistirex; hydrocodone polistirex)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Promethazine:
- not at all: 3.03 %
- somewhat: 19.77 %
- moderate: 35.67 %
- high: 28.29 %
- very high: 13.25 %
Tussicaps:
- not at all: 4.72 %
- somewhat: 26.42 %
- moderate: 31.13 %
- high: 26.42 %
- very high: 11.32 %
Want to compare Promethazine with Tussicaps?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
Related studies
Alternative drugs to, pros and cons of:
- Promethazine (31,263 reports)
- Tussicaps (44 reports)
Browse all side effects of Promethazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tussicaps:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on promethazine hydrochloride and chlorpheniramine polistirex; hydrocodone polistirex (the active ingredients of Promethazine and Tussicaps, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Simponi and Psoriatic Arthropathy for Men aged 60+ - 4 seconds ago
- Back Pain - Low in Coreg, how severe and when it was recovered? - 30 seconds ago
- Vitamin B1 vs. Adderall Xr 10, side effect and effectiveness comparison - 49 seconds ago
- Amiodarone Hydrochloride and Atrial Fibrillation/Flutter for Women aged 60+ - 51 seconds ago
- Amiodarone Hydrochloride and Heart Fibrillation for Women aged 60+ - 51 seconds ago
- Amiodarone Hydrochloride and Atrial Flutter for Women aged 60+ - 51 seconds ago
- Amiodarone Hydrochloride and Atrial Fibrillation for Women aged 60+ - 51 seconds ago
- Amiodarone Hydrochloride and A-Fib for Women aged 60+ - 52 seconds ago
- Amiodarone Hydrochloride and Auricular Fibrillation for Women aged 60+ - 52 seconds ago
- Could Depakote cause Seborrhea? - a minute ago