Delsym vs. Promethazine with codeine: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Delsym and Promethazine with codeine. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 13,287 people who take Delsym and Promethazine with codeine, and is updated regularly.
What is Delsym?
Delsym has active ingredients of dextromethorphan polistirex. It is often used in cough. eHealthMe is studying from 5,033 Delsym users. Check the latest studies of Delsym.
What is Promethazine with codeine?
Promethazine with codeine has active ingredients of codeine phosphate; promethazine hydrochloride. It is often used in cough. eHealthMe is studying from 269 Promethazine with codeine users. Check the latest studies of Promethazine with codeine.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
13,287 people who take Delsym and Promethazine with codeine are studied.

Drugs being compared in this study:
- Delsym (dextromethorphan polistirex)
- Promethazine With Codeine (codeine phosphate; promethazine hydrochloride)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Delsym:
- not at all: 4.82 %
- somewhat: 40.36 %
- moderate: 28.92 %
- high: 19.28 %
- very high: 6.63 %
Promethazine With Codeine:
- not at all: 6.33 %
- somewhat: 29.11 %
- moderate: 32.91 %
- high: 24.05 %
- very high: 7.59 %
Want to compare Delsym with Promethazine with codeine?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related studies
Alternative drugs to, pros and cons of:
- Delsym (4,675 reports)
- Promethazine with codeine (219 reports)
Browse all side effects of Delsym:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Promethazine with codeine:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on dextromethorphan polistirex and codeine phosphate; promethazine hydrochloride (the active ingredients of Delsym and Promethazine with codeine, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Seroquel cause Aseptic Necrosis? - 4 seconds ago
- Could Clarithromycin cause Haematuria Present? - 5 seconds ago
- Remeron vs. Vitamin D, side effect and effectiveness comparison - 12 seconds ago
- Could Clarinex cause Ards (Acute Respiratory Distress Syndrome)? - 14 seconds ago
- Could Estradiol cause Folliculitis? - 18 seconds ago
- Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Migraine - 19 seconds ago
- Could Adalat cause Blindness? - 19 seconds ago
- Could Acyclovir cause Conjunctivitis? - 20 seconds ago
- Acute Coronary Syndrome and Diverticulitis - 20 seconds ago
- Could Acyclovir cause Bone Pain Aggravated? - 20 seconds ago