Reglan vs. Senna: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Reglan and Senna. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 147,062 people who take Reglan and Senna, and is updated regularly.
What is Reglan?
Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.
What is Senna?
Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
147,062 people who take Reglan and Senna are studied.

Drugs being compared in this study:
- Reglan (metoclopramide hydrochloride)
- Senna (senna)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Reglan:
- not at all: 5.42 %
- somewhat: 34.32 %
- moderate: 33.17 %
- high: 20.69 %
- very high: 6.4 %
Senna:
- not at all: 2.89 %
- somewhat: 11.85 %
- moderate: 39.88 %
- high: 22.83 %
- very high: 22.54 %
Want to compare Reglan with Senna?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related studies
Alternative drugs to, pros and cons of:
Browse all side effects of Reglan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Senna:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on metoclopramide hydrochloride and senna (the active ingredients of Reglan and Senna, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Coreg cause Swallowing Difficulty? - 10 seconds ago
- Accupril and Diabetes Mellitus Aggravated for Women aged 40-49 - 14 seconds ago
- Could Carvedilol cause Fluid Overload? - 32 seconds ago
- Mirapex and Nexium drug interactions for men aged 50-59 - a minute ago
- Could Tacrolimus cause Common Peroneal Nerve Dysfunction? - a minute ago
- Drug interactions of Vitamin B12 and Ajovy - a minute ago
- Hydroxychloroquine Sulfate and Methotrexate drug interactions for boys aged 10-19 - 2 minutes ago
- Could Anzemet cause Chills? - 2 minutes ago
- Humira and Probiotics drug interactions for men aged 60+ - 2 minutes ago
- Quetiapine Fumarate and Pituitary Tumor Benign for Women aged 30-39 - 2 minutes ago