Simponi vs. Tramadol hydrochloride: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Simponi and Tramadol hydrochloride. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 354,151 people who take Simponi and Tramadol hydrochloride, and is updated regularly.
What is Simponi?
Simponi has active ingredients of golimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 86,328 Simponi users. Check the latest studies of Simponi.
What is Tramadol hydrochloride?
Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 40,749 Tramadol hydrochloride users. Check the latest studies of Tramadol hydrochloride.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
354,151 people who take Simponi and Tramadol hydrochloride are studied.

Drugs being compared in this study:
- Tramadol Hydrochloride (tramadol hydrochloride)
- Simponi (golimumab)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Simponi:
- not at all: 3.3 %
- somewhat: 22.53 %
- moderate: 28.02 %
- high: 32.42 %
- very high: 13.74 %
Tramadol Hydrochloride:
- not at all: 3.44 %
- somewhat: 25.84 %
- moderate: 41.66 %
- high: 22.99 %
- very high: 6.08 %
Want to compare Simponi with Tramadol hydrochloride?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
- Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
Related studies
Alternative drugs to, pros and cons of:
- Simponi (86,114 reports)
- Tramadol hydrochloride (38,317 reports)
Browse all side effects of Simponi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tramadol hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on golimumab and tramadol hydrochloride (the active ingredients of Simponi and Tramadol hydrochloride, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Spravato cause Nasopharyngitis? - 5 seconds ago
- Could Concerta cause Head Discomfort? - 7 seconds ago
- Drug interactions of Minoxidil and Pradaxa - 15 seconds ago
- Mouth Ulceration Aggravated in Adderall Xr 25, how severe and when it was recovered? - 17 seconds ago
- Invokana and Novolog drug interactions for women aged 60+ - 32 seconds ago
- Could Combivent cause Pharyngitis Streptococcal? - 35 seconds ago
- Could Meclizine cause Nasal Septum Deviation? - 39 seconds ago
- Could Levoleucovorin Calcium cause Hypomagnesaemia? - 40 seconds ago
- Could Cilostazol cause Multi-Organ Failure? - 42 seconds ago
- Could Rexulti cause Energy Increased? - 52 seconds ago