Treximet vs. Frova: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Treximet and Frova. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 35,462 people who take Treximet and Frova, and is updated regularly.
What is Treximet?
Treximet has active ingredients of naproxen sodium; sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 1,904 Treximet users. Check the latest studies of Treximet.
What is Frova?
Frova has active ingredients of frovatriptan succinate. It is often used in migraine. eHealthMe is studying from 2,100 Frova users. Check the latest studies of Frova.
35,462 people who take Treximet and Frova are studied.

Drugs being compared in this study:
- Treximet (naproxen sodium; sumatriptan succinate)
- Frova (frovatriptan succinate)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Treximet:
- not at all: 3.01 %
- somewhat: 17.29 %
- moderate: 24.06 %
- high: 38.35 %
- very high: 17.29 %
Frova:
- not at all: 3.66 %
- somewhat: 19.51 %
- moderate: 31.71 %
- high: 29.27 %
- very high: 15.85 %
Want to compare Treximet with Frova?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related studies
Alternative drugs to, pros and cons of:
Browse all side effects of Treximet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Frova:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on naproxen sodium; sumatriptan succinate and frovatriptan succinate (the active ingredients of Treximet and Frova, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Amoxicillin and Eylea drug interactions for women aged 60+ - 3 seconds ago
- Could Synthroid cause Optic Neuropathy? - 4 seconds ago
- Could Prochlorperazine Maleate cause Throat Tightness? - 20 seconds ago
- Could Tasigna cause Haematuria? - 20 seconds ago
- Cardizem Sr vs. Benicar Hct, side effect and effectiveness comparison - 24 seconds ago
- Asthmatic Crisis and drugs of ingredients of ciclesonide - 30 seconds ago
- Hydrocodone Bitartrate And Homatropine Methylbromide vs. Flovent, side effect and effectiveness comparison - 31 seconds ago
- Tachycardia Aggravated and Blood Pressure Abnormal - 32 seconds ago
- Rheumatoid Arthritis and drugs of ingredients of acetylcysteine - 33 seconds ago
- Lamictal Odt vs. Bupropion Hydrochloride, side effect and effectiveness comparison - a minute ago