Prozac vs. Trintellix: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Prozac and Trintellix. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 198,928 people who take Prozac and Trintellix, and is updated regularly.
What is Prozac?
Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,974 Prozac users. Check the latest studies of Prozac.
What is Trintellix?
Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,064 Trintellix users. Check the latest studies of Trintellix.
198,928 people who take Prozac and Trintellix are studied.
Drugs being compared in this study:
- Prozac (fluoxetine hydrochloride)
- Trintellix (vortioxetine hydrobromide)
Most common side effects of the drugs, overall:
Prozac:
- Nausea (feeling of having an urge to vomit)
- Fatigue (feeling of tiredness)
- Drug Ineffective
- Headache (pain in head)
- Pain
- Dyspnoea (difficult or laboured respiration)
- Diarrhoea
- Vomiting
- Dizziness
- Fall
Trintellix:
- Nausea (feeling of having an urge to vomit)
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Vomiting
- Suicidal Ideation
- Drug Ineffective
- Dizziness
- Insomnia (sleeplessness)
- Weight Increased
- Diarrhoea
Most common side effects of the drugs, in long term (1+ years) use:
Prozac:
- Chronic Kidney Disease
- Pain
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Suicidal Ideation
- Dizziness
- Renal Failure (kidney dysfunction)
- Drug Ineffective
- Weight Increased
- Insomnia (sleeplessness)
Trintellix:
- Nausea (feeling of having an urge to vomit)
- Suicidal Ideation
- Fatigue (feeling of tiredness)
- Pain
- Vomiting
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Dizziness
- Diarrhoea
- Pancreatitis (inflammation of pancreas)
- Drug Ineffective
Drug effectiveness:
Prozac:
- not at all: 4.68 %
- somewhat: 21.01 %
- moderate: 35.94 %
- high: 29.7 %
- very high: 8.67 %
Trintellix:
- not at all: 5.22 %
- somewhat: 22.12 %
- moderate: 37.17 %
- high: 26.88 %
- very high: 8.6 %
Want to compare Prozac with Trintellix?
Personalize this study to your gender and age (0-99+).How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related studies
Alternative drugs to, pros and cons of:
- Prozac (74,864 reports)
- Trintellix (12,454 reports)
Common Prozac side effects:
- Depression: 5,709 reports
- Headache (pain in head): 4,772 reports
- Dyspnea (difficult or laboured breathing): 3,963 reports
Browse all side effects of Prozac:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Trintellix side effects:
- Insomnia (sleeplessness): 607 reports
- Drug ineffective: 606 reports
Browse all side effects of Trintellix:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on fluoxetine hydrochloride and vortioxetine hydrobromide (the active ingredients of Prozac and Trintellix, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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