Trokendi xr vs. Sumatriptan: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Trokendi xr and Sumatriptan. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 118,098 people who take Trokendi xr and Sumatriptan, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
118,098 people who take Trokendi xr and Sumatriptan are studied.
What is Trokendi xr?
Trokendi xr has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 1,474 Trokendi xr users for its effectiveness, alternative drugs and more.
What is Sumatriptan?
Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 10,718 Sumatriptan users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:
Drugs being compared in this study:
- Trokendi Xr (topiramate)
- Sumatriptan (sumatriptan succinate)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Trokendi Xr:
- not at all: 4.54 %
- somewhat: 22.08 %
- moderate: 30.91 %
- high: 29.2 %
- very high: 13.26 %
Sumatriptan:
- not at all: 1.8599999999999999 %
- somewhat: 12.5 %
- moderate: 22.69 %
- high: 35.27 %
- very high: 27.68 %
Want to compare Trokendi xr with Sumatriptan?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
Related studies
Alternative drugs to, pros and cons of:
- Trokendi xr (1,436 reports)
- Sumatriptan (9,866 reports)
Common Trokendi xr side effects:
- Drug ineffective: 192 reports
- Headache (pain in head): 143 reports
- Memory loss: 126 reports
- Migraine (headache): 150 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 112 reports
Common Sumatriptan side effects:
- Abdominal discomfort: 108 reports
- Abdominal pain: 158 reports
- Abdominal pain upper: 117 reports
- Back pain: 164 reports
- Breathing difficulty: 408 reports
- Chest pain: 380 reports
- Chronic kidney disease: 109 reports
- Confusional state: 141 reports
- Constipation: 105 reports
- Cough: 105 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 106 reports
- Depression: 275 reports
- Diarrhea: 295 reports
- Dizziness: 430 reports
- Drowsiness: 249 reports
- Drug hypersensitivity: 240 reports
- Drug ineffective: 1,481 reports
- Drug intolerance (drug sensitivity): 142 reports
- Emotional distress: 103 reports
- Fall: 241 reports
- Fatigue (feeling of tiredness): 546 reports
- Fever: 203 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 103 reports
- Hair loss: 118 reports
- Headache (pain in head): 715 reports
- Head injury: 138 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 139 reports
- High blood pressure: 394 reports
- Hot flush (sudden feelings of heat): 150 reports
- Hyperhidrosis (abnormally increased sweating): 160 reports
- Hypersensitivity: 119 reports
- Hypoaesthesia (reduced sense of touch or sensation): 220 reports
- Hypotension (abnormally low blood pressure): 148 reports
- Injection site pain: 202 reports
- Injury: 109 reports
- Insomnia (sleeplessness): 191 reports
- Itching: 164 reports
- Joint pain: 298 reports
- Joint swelling: 129 reports
- Loss of consciousness: 142 reports
- Malaise (a feeling of general discomfort or uneasiness): 317 reports
- Memory loss: 212 reports
- Migraine (headache): 769 reports
- Muscle aches (muscle pain): 105 reports
- Muscle spasms (muscle contraction): 151 reports
- Nausea (feeling of having an urge to vomit): 742 reports
- Nausea and vomiting: 390 reports
- Oedema peripheral (superficial swelling): 104 reports
- Overdose: 117 reports
- Pain: 563 reports
- Pain in extremity: 182 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 213 reports
- Pneumonia: 127 reports
- Pulmonary embolism (blockage of the main artery of the lung): 104 reports
- Rashes (redness): 227 reports
- Sinusitis (inflammation of sinus): 104 reports
- Skin blushing/flushing (a sudden reddening of the face, neck): 116 reports
- Stress and anxiety: 468 reports
- Suicidal ideation: 117 reports
- Therapeutic response decreased (less preventive response): 141 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 181 reports
- Urinary tract infection: 126 reports
- Weakness: 277 reports
- Weight decreased: 196 reports
- Weight increased: 141 reports
How the study uses the data?
The study is based on topiramate and sumatriptan succinate (the active ingredients of Trokendi xr and Sumatriptan, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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