Vicodin es vs. Prialt: side effect and effectiveness comparison (a real world drug study)

Summary:

We compare the side effects and drug effectiveness of Vicodin es and Prialt. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 304,962 people who take Vicodin es and Prialt, and is updated regularly.

What is Vicodin es?

Vicodin es has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 2,450 Vicodin es users. Check the latest studies of Vicodin es.

What is Prialt?

Prialt has active ingredients of ziconotide. It is often used in pain. eHealthMe is studying from 2,665 Prialt users. Check the latest studies of Prialt.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 20, 2026

304,962 people who take Vicodin es and Prialt are studied.

Vicodin es vs Prialt drug comparison reports.

Drugs being compared in this study:

  • Prialt (ziconotide)
  • Vicodin Es (acetaminophen; hydrocodone bitartrate)

Most common side effects of the drugs, overall:

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Most common side effects of the drugs, in long term (1+ years) use:

Click here to view

Drug effectiveness:

Vicodin Es:

  • not at all: 1.4 %
  • somewhat: 21.44 %
  • moderate: 41.19 %
  • high: 27.5 %
  • very high: 8.47 %

Prialt:

  • not at all: 5.88 %
  • somewhat: 17.65 %
  • moderate: 29.41 %
  • high: 17.65 %
  • very high: 29.41 %

Want to compare Vicodin es with Prialt?

- Personalize this study to your gender and age (0-99+)

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.



Related studies

Alternative drugs to, pros and cons of:

Browse all side effects of Vicodin es:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prialt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study is based on acetaminophen; hydrocodone bitartrate and ziconotide (the active ingredients of Vicodin es and Prialt, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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