Zopiclone vs. Tranxene: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Zopiclone and Tranxene. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 92,184 people who take Zopiclone and Tranxene, and is updated regularly.
What is Zopiclone?
Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 54,330 Zopiclone users. Check the latest studies of Zopiclone.
What is Tranxene?
Tranxene has active ingredients of clorazepate dipotassium. It is often used in stress and anxiety. eHealthMe is studying from 6,550 Tranxene users. Check the latest studies of Tranxene.
92,184 people who take Zopiclone and Tranxene are studied.

Drugs being compared in this study:
- Tranxene (clorazepate dipotassium)
- Zopiclone (eszopiclone)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Zopiclone:
- not at all: 3.67 %
- somewhat: 15.97 %
- moderate: 35.64 %
- high: 31.71 %
- very high: 13.01 %
Tranxene:
- not at all: 7.76 %
- somewhat: 18.97 %
- moderate: 37.07 %
- high: 23.28 %
- very high: 12.93 %
Want to compare Zopiclone with Tranxene?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
- Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
Related studies
Alternative drugs to, pros and cons of:
Browse all side effects of Zopiclone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tranxene:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on eszopiclone and clorazepate dipotassium (the active ingredients of Zopiclone and Tranxene, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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