Clostridium colitis and drugs of ingredients of acyclovir (a real world drug study)


Summary:

Clostridium colitis is found among people who take drugs with ingredients of acyclovir, especially for people who are male, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 60,076 people who have side effects when taking drugs with ingredients of acyclovir from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Acyclovir, Avaclyr, Sitavig.

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On Jun, 01, 2026

60,076 people reported to have side effects when taking drugs with ingredients of acyclovir.
Among them, 29 people (0.05%) have Clostridium colitis


What is Clostridium colitis?

Clostridium colitis (inflammation of colon by clostridium difficile bacteria infection) is found to be associated with 236 drugs and 503 conditions by eHealthMe. Check the latest studies of Clostridium colitis.

Number of reports submitted per year:

Could drugs with ingredients of acyclovir cause Clostridium colitis?

Time on drugs with ingredients of acyclovir when people have Clostridium colitis *:

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 50 %
  • 10+ years: 0.0 %

Gender of people who have Clostridium colitis when taking drugs with ingredients of acyclovir *:

  • female: 48.28 %
  • male: 51.72 %

Age of people who have Clostridium colitis when taking drugs with ingredients of acyclovir *:

  • 0-1: 12 %
  • 2-9: 0.0 %
  • 10-19: 4 %
  • 20-29: 4 %
  • 30-39: 0.0 %
  • 40-49: 20 %
  • 50-59: 20 %
  • 60+: 40 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Multiple Myeloma (cancer of the plasma cells): 7 people, 24.14%
  2. Pneumonia: 4 people, 13.79%
  3. Secondary Immunodeficiency (lack of immunity due to some disease): 1 person, 3.45%
  4. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 1 person, 3.45%
  5. Respiratory Syncytial Virus Infection (viral disease of respiratory system): 1 person, 3.45%
  6. Hypertriglyceridaemia (excess of triglycerides in the blood): 1 person, 3.45%
  7. Hiv Infection: 1 person, 3.45%
  8. High Density Lipoprotein Decreased: 1 person, 3.45%
  9. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 3.45%
  10. Bacterial Sepsis: 1 person, 3.45%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Etoposide: 10 people, 34.48%
  2. Cyclophosphamide: 9 people, 31.03%
  3. Dexamethasone: 8 people, 27.59%
  4. Thalomid: 7 people, 24.14%
  5. Vancomycin: 6 people, 20.69%
  6. Protonix: 6 people, 20.69%
  7. Diflucan: 6 people, 20.69%
  8. Zoloft: 5 people, 17.24%
  9. Cisplatin: 5 people, 17.24%
  10. Digoxin: 5 people, 17.24%

Other side effects people have besides Clostridium colitis *:

You may use this to check any potential undetected side effects.

  1. Pneumonia: 12 people, 41.38%
  2. Fever: 11 people, 37.93%
  3. Nausea (feeling of having an urge to vomit): 8 people, 27.59%
  4. Weakness: 7 people, 24.14%
  5. Tachypnea: 7 people, 24.14%
  6. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 24.14%
  7. Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 20.69%
  8. Haemoglobin Decreased: 6 people, 20.69%
  9. Blood Lactate Dehydrogenase Increased: 6 people, 20.69%
  10. Thrombocytopenia (decrease of platelets in blood): 6 people, 20.69%

* Approximation only. Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

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How the study uses the data?

The study uses data from the FDA. It is based on acyclovir. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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