Scleroderma and drugs of ingredients of acyclovir (a real world drug study)


Summary:

Scleroderma is found among people who take drugs with ingredients of acyclovir, especially for people who are male, 60+ old . This phase IV clinical study is created by eHealthMe based on reports of 60,076 people who have side effects when taking drugs with ingredients of acyclovir from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Acyclovir, Avaclyr, Sitavig.


On Apr, 19, 2026

60,076 people reported to have side effects when taking drugs with ingredients of acyclovir.
Among them, 19 people (0.03%) have Scleroderma


What is Scleroderma?

Scleroderma (hard skin) is found to be associated with 940 drugs and 856 conditions by eHealthMe. Check the latest studies of Scleroderma.

Number of reports submitted per year:

Could drugs with ingredients of acyclovir cause Scleroderma?

Gender of people who have Scleroderma when taking drugs with ingredients of acyclovir *:

  • female: 37.5 %
  • male: 62.5 %

Age of people who have Scleroderma when taking drugs with ingredients of acyclovir *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 7.14 %
  • 40-49: 14.29 %
  • 50-59: 35.71 %
  • 60+: 42.86 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Nuclear Magnetic Resonance Imaging Brain: 5 people, 26.32%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 10.53%
  3. Nuclear Magnetic Resonance Imaging Abdominal: 2 people, 10.53%
  4. Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 2 people, 10.53%
  5. Osteoporosis (bones weak and more likely to break): 1 person, 5.26%
  6. Neoplasm Malignant (cancer tumour): 1 person, 5.26%
  7. Ill-Defined Disorder: 1 person, 5.26%
  8. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 5.26%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Prednisone: 9 people, 47.37%
  2. Ergocalciferol: 7 people, 36.84%
  3. Fluconazole: 6 people, 31.58%
  4. Hectorol: 5 people, 26.32%
  5. Inderal: 5 people, 26.32%
  6. Venofer: 5 people, 26.32%
  7. Fosrenol: 5 people, 26.32%
  8. Midodrine Hydrochloride: 5 people, 26.32%
  9. Multihance: 5 people, 26.32%
  10. Omniscan: 5 people, 26.32%

Other side effects people have besides Scleroderma *:

You may use this to check any potential undetected side effects.

  1. Rashes (redness): 7 people, 36.84%
  2. Pain: 6 people, 31.58%
  3. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 6 people, 31.58%
  4. Joint Pain: 6 people, 31.58%
  5. Pleural Fibrosis (formation of fibrous tissue in lung): 6 people, 31.58%
  6. Gait Disturbance: 6 people, 31.58%
  7. Mobility Decreased (ability to move is reduced): 5 people, 26.32%
  8. Subcutaneous Nodule: 5 people, 26.32%
  9. Skin Tightness: 5 people, 26.32%
  10. Skin Plaque (red, scaly patches to appear on the skin): 5 people, 26.32%

* Approximation only. Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

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How the study uses the data?

The study uses data from the FDA. It is based on acyclovir. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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