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Rectal bleeding and drugs of ingredients of amitriptyline hydrochloride - a phase IV clinical study of FDA data


Summary:

Rectal bleeding is found among people who take drugs with ingredients of amitriptyline hydrochloride, especially for people who are female, 40-49 old . This phase IV clinical study is created by eHealthMe based on reports of 110,446 people who have side effects when taking drugs with ingredients of amitriptyline hydrochloride from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Amitid, Amitril, Amitriptyline hydrochloride, Elavil, Endep.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Apr, 02, 2023

110,446 people reported to have side effects when taking drugs with ingredients of amitriptyline hydrochloride.
Among them, 60 people (0.05%) have Rectal bleeding

What is Rectal bleeding?

Rectal bleeding (bleeding from rectum) is found to be associated with 899 drugs and 10 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of amitriptyline hydrochloride cause Rectal bleeding?

Gender of people who have Rectal bleeding when taking drugs with ingredients of amitriptyline hydrochloride *:

  • female: 71.67 %
  • male: 28.33 %

Age of people who have Rectal bleeding when taking drugs with ingredients of amitriptyline hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5.26 %
  • 30-39: 12.28 %
  • 40-49: 40.35 %
  • 50-59: 21.05 %
  • 60+: 21.05 %

Other drugs people take *:

  1. Celebrex: 15 people, 25.00%
  2. Premarin: 9 people, 15.00%
  3. Prednisone: 8 people, 13.33%
  4. Lipitor: 7 people, 11.67%
  5. Lorazepam: 7 people, 11.67%
  6. Vicodin: 7 people, 11.67%
  7. Compazine: 7 people, 11.67%
  8. Morphine: 6 people, 10.00%
  9. Paxil: 6 people, 10.00%
  10. Prilosec: 6 people, 10.00%

Other side effects people have besides Rectal bleeding *:

  1. Weight Decreased: 10 people, 16.67%
  2. Colitis Ischaemic (due to infection of intestine impaired blood supply to colon): 10 people, 16.67%
  3. Hypotension (abnormally low blood pressure): 8 people, 13.33%
  4. Chest Pain: 8 people, 13.33%
  5. Nausea (feeling of having an urge to vomit): 8 people, 13.33%
  6. Haemoglobin Decreased: 7 people, 11.67%
  7. Thrombocytopenia (decrease of platelets in blood): 7 people, 11.67%
  8. Weakness: 6 people, 10.00%
  9. Fever: 6 people, 10.00%
  10. Blood In Stool: 6 people, 10.00%

* Approximation only. Some reports may have incomplete information.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Drugs with ingredients of amitriptyline hydrochloride, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on amitriptyline hydrochloride. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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