Constipation and drugs of ingredients of aprepitant (a real world drug study)


Summary:

Constipation is found among people who take drugs with ingredients of aprepitant, especially for people who are female, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 20,492 people who have side effects when taking drugs with ingredients of aprepitant from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Aponvie, Aprepitant, Cinvanti, Emend.


On Nov, 13, 2025

20,492 people reported to have side effects when taking drugs with ingredients of aprepitant.
Among them, 708 people (3.46%) have Constipation


What is Constipation?

Constipation is found to be associated with 3,002 drugs and 4,564 conditions by eHealthMe. Check the latest studies of Constipation.

Number of reports submitted per year:

Could drugs with ingredients of aprepitant cause Constipation?

Time on drugs with ingredients of aprepitant when people have Constipation *:

  • < 1 month: 74.13 %
  • 1 - 6 months: 23.55 %
  • 6 - 12 months: 2.32 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Constipation when taking drugs with ingredients of aprepitant *:

  • female: 64.4 %
  • male: 35.6 %

Age of people who have Constipation when taking drugs with ingredients of aprepitant *:

  • 0-1: 0.0 %
  • 2-9: 0.37 %
  • 10-19: 3.32 %
  • 20-29: 1.6600000000000001 %
  • 30-39: 5.9 %
  • 40-49: 16.24 %
  • 50-59: 29.34 %
  • 60+: 43.17 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. High Blood Pressure: 85 people, 12.01%
  2. Breast Cancer: 85 people, 12.01%
  3. Pain: 72 people, 10.17%
  4. Colon Cancer: 51 people, 7.20%
  5. Wheezing (a high-pitched whistling sound made while you breath): 48 people, 6.78%
  6. Cough: 47 people, 6.64%
  7. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 47 people, 6.64%
  8. Diarrhea: 46 people, 6.50%
  9. Headache (pain in head): 45 people, 6.36%
  10. Mucosal Inflammation (infection of mucous membrane): 42 people, 5.93%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Ondansetron: 245 people, 34.60%
  2. Dexamethasone: 137 people, 19.35%
  3. Avastin: 111 people, 15.68%
  4. Neulasta: 108 people, 15.25%
  5. Decadron: 94 people, 13.28%
  6. Taxotere: 91 people, 12.85%
  7. Acetaminophen: 88 people, 12.43%
  8. Aloxi: 81 people, 11.44%
  9. Cisplatin: 80 people, 11.30%
  10. Zofran: 74 people, 10.45%

Other side effects people have besides Constipation *:

You may use this to check any potential undetected side effects.

  1. Fatigue (feeling of tiredness): 271 people, 38.28%
  2. Diarrhea: 187 people, 26.41%
  3. Abdominal Pain: 157 people, 22.18%
  4. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 146 people, 20.62%
  5. Hair Loss: 143 people, 20.20%
  6. Rashes (redness): 137 people, 19.35%
  7. Neuropathy Peripheral (surface nerve damage): 128 people, 18.08%
  8. Nausea And Vomiting: 127 people, 17.94%
  9. Weight Decreased: 126 people, 17.80%
  10. Headache (pain in head): 116 people, 16.38%

* Approximation only. Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of aprepitant, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on aprepitant. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: