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Second primary malignancy and drugs of ingredients of carmustine (a real world drug study)


Summary:

Second primary malignancy is found among people who take drugs with ingredients of carmustine, especially for people who are male, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 6,477 people who have side effects when taking drugs with ingredients of carmustine from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Bicnu, Carmustine, Gliadel.

On Jun, 19, 2026

6,477 people reported to have side effects when taking drugs with ingredients of carmustine.
Among them, 170 people (2.62%) have Second primary malignancy

What is Second primary malignancy?

Second primary malignancy (after getting cure a cancer, a new cancer development) is found to be associated with 537 drugs and 467 conditions by eHealthMe. Check the latest studies of Second primary malignancy.

Number of reports submitted per year:

Could drugs with ingredients of carmustine cause Second primary malignancy?

Time on drugs with ingredients of carmustine when people have Second primary malignancy *:

  • < 1 month: 85.19 %
  • 1 - 6 months: 3.7 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 3.7 %
  • 2 - 5 years: 7.41 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Second primary malignancy when taking drugs with ingredients of carmustine *:

  • female: 24.83 %
  • male: 75.17 %

Age of people who have Second primary malignancy when taking drugs with ingredients of carmustine *:

  • 0-1: 0.78 %
  • 2-9: 1.55 %
  • 10-19: 0.78 %
  • 20-29: 1.55 %
  • 30-39: 21.71 %
  • 40-49: 14.73 %
  • 50-59: 22.48 %
  • 60+: 36.43 %

Conditions people have *:

You may use this to check any potential undetected conditions.

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Other drugs people take *:

You may use this to check any potential interacting drugs.

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Other side effects people have besides Second primary malignancy *:

You may use this to check any potential undetected side effects.

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* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

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How the study uses the data?

The study uses data from the FDA. It is based on carmustine. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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