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Liver function test abnormal and drugs of ingredients of codeine sulfate (a real world drug study)


Summary:

Liver function test abnormal is found among people who take drugs with ingredients of codeine sulfate, especially for people who are female, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 41,713 people who have side effects when taking drugs with ingredients of codeine sulfate from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Codeine, Codeine sulfate.

On Dec, 22, 2025

41,713 people reported to have side effects when taking drugs with ingredients of codeine sulfate.
Among them, 318 people (0.76%) have Liver function test abnormal

What is Liver function test abnormal?

Liver function test abnormal is found to be associated with 1,535 drugs and 1,944 conditions by eHealthMe. Check the latest studies of Liver function test abnormal.

Number of reports submitted per year:

Could drugs with ingredients of codeine sulfate cause Liver function test abnormal?

Time on drugs with ingredients of codeine sulfate when people have Liver function test abnormal *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Liver function test abnormal when taking drugs with ingredients of codeine sulfate *:

  • female: 84.48 %
  • male: 15.52 %

Age of people who have Liver function test abnormal when taking drugs with ingredients of codeine sulfate *:

  • 0-1: 5.41 %
  • 2-9: 0.0 %
  • 10-19: 6.31 %
  • 20-29: 3.6 %
  • 30-39: 1.8 %
  • 40-49: 5.86 %
  • 50-59: 11.26 %
  • 60+: 65.77 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 187 people, 58.81%
  2. Joint Pain: 35 people, 11.01%
  3. High Blood Cholesterol: 19 people, 5.97%
  4. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 16 people, 5.03%
  5. Back Disorder: 13 people, 4.09%
  6. Kidney Infection (Pyelonephritis): 13 people, 4.09%
  7. Pelvic Pain: 13 people, 4.09%
  8. Anaesthesia: 10 people, 3.14%
  9. Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 10 people, 3.14%
  10. Hepatic Pain (pain in liver): 10 people, 3.14%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Ativan: 193 people, 60.69%
  2. Dilaudid: 189 people, 59.43%
  3. Arava: 183 people, 57.55%
  4. Xeljanz: 182 people, 57.23%
  5. Humira: 182 people, 57.23%
  6. Vagifem: 181 people, 56.92%
  7. Synthroid: 181 people, 56.92%
  8. Enbrel: 179 people, 56.29%
  9. Orencia: 178 people, 55.97%
  10. Restasis: 176 people, 55.35%

Other side effects people have besides Liver function test abnormal *:

You may use this to check any potential undetected side effects.

  1. High Blood Cholesterol: 188 people, 59.12%
  2. Anaemia (lack of blood): 186 people, 58.49%
  3. Peripheral Swelling: 183 people, 57.55%
  4. Leukopenia (less number of white blood cells in blood): 183 people, 57.55%
  5. Herpes Zoster: 182 people, 57.23%
  6. Fibromyalgia (a long-term condition which causes pain all over the body): 182 people, 57.23%
  7. Synovitis (inflammation of the synovial membrane): 181 people, 56.92%
  8. Infection: 181 people, 56.92%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 176 people, 55.35%
  10. Joint Swelling: 173 people, 54.40%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of codeine sulfate, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on codeine sulfate. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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