Lymphoma and drugs of ingredients of deferasirox (a real world drug study)
Summary:
Lymphoma is found among people who take drugs with ingredients of deferasirox, especially for people who are male, 60+ old , have been taking the drugs for 1 - 2 years. This phase IV clinical study is created by eHealthMe based on reports of 35,743 people who have side effects when taking drugs with ingredients of deferasirox from the FDA, and is updated regularly.
Drug(s) considered in the study (i.e. both brand name and generic drugs): Deferasirox, Exjade, Jadenu, Jadenu sprinkle.
35,743 people reported to have side effects when taking drugs with ingredients of deferasirox.
Among them, 38 people (0.11%) have Lymphoma
What is Lymphoma?
Lymphoma (cancer that begins in immune system cells) is found to be associated with 960 drugs and 1,014 conditions by eHealthMe. Check the latest studies of Lymphoma.
Number of reports submitted per year:

Time on drugs with ingredients of deferasirox when people have Lymphoma *:
- < 1 month: 14.29 %
- 1 - 6 months: 14.29 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 42.86 %
- 2 - 5 years: 28.57 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Lymphoma when taking drugs with ingredients of deferasirox *:
- female: 42.86 %
- male: 57.14 %
Age of people who have Lymphoma when taking drugs with ingredients of deferasirox *:
- 0-1: 0.0 %
- 2-9: 5.26 %
- 10-19: 0.0 %
- 20-29: 5.26 %
- 30-39: 5.26 %
- 40-49: 10.53 %
- 50-59: 15.79 %
- 60+: 57.89 %
Conditions people have *:
You may use this to check any potential undetected conditions.
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 10.53%
- Serum Ferritin Increased: 3 people, 7.89%
- Lymphoproliferative Disorder (a medical condition in which the immune system makes too many white blood cells): 3 people, 7.89%
- High Blood Pressure: 2 people, 5.26%
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 5.26%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.26%
- Gastric Ulcer (stomach ulcer): 1 person, 2.63%
- Aplastic Anemia: 1 person, 2.63%
- Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 1 person, 2.63%
- Bladder Mass: 1 person, 2.63%
Other drugs people take *:
You may use this to check any potential interacting drugs.
- Dipyrone: 3 people, 7.89%
- Amlodipine: 2 people, 5.26%
- Nexium: 2 people, 5.26%
- Vitamin D: 1 person, 2.63%
- Hydrea: 1 person, 2.63%
- Actos: 1 person, 2.63%
- Aranesp: 1 person, 2.63%
- Ciclosporin: 1 person, 2.63%
- Flovent: 1 person, 2.63%
- Folic Acid: 1 person, 2.63%
Other side effects people have besides Lymphoma *:
You may use this to check any potential undetected side effects.
- Dyspnea (difficult or laboured breathing): 6 people, 15.79%
- Serum Ferritin Increased: 6 people, 15.79%
- Haemoglobin Decreased: 6 people, 15.79%
- Malaise (a feeling of general discomfort or uneasiness): 6 people, 15.79%
- Nausea (feeling of having an urge to vomit): 6 people, 15.79%
- Abdominal Pain: 5 people, 13.16%
- Nausea And Vomiting: 5 people, 13.16%
- Weight Decreased: 5 people, 13.16%
- Drug Ineffective: 5 people, 13.16%
- Fatigue (feeling of tiredness): 5 people, 13.16%
* Approximation only. Some reports may have incomplete information.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
- Díaz-García JD, Gallegos-Villalobos A, Gonzalez-Espinoza L, Sanchez-Ni?o MD, Villarrubia J, Ortiz A, "Deferasirox nephrotoxicity [mdash] the knowns and unknowns", Nature reviews nephrology, 2014 Oct .
- Riva A, "Comment on: A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Expert opinion on drug safety, 2013 Sep .
- Riva A, "Deferasirox's toxicity", The Lancet, 2013 Jul .
- Kontoghiorghes GJ, "Turning a blind eye to deferasirox's toxicity?", The Lancet, 2013 Apr .
- Kontoghiorghes GJ, "A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Taylor & Francis, 2013 Jan .
- Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
- Díaz-García JD, Gallegos-Villalobos A, Gonzalez-Espinoza L, Sanchez-Ni?o MD, Villarrubia J, Ortiz A, "Deferasirox nephrotoxicity [mdash] the knowns and unknowns", Nature reviews nephrology, 2014 Oct .
- Riva A, "Comment on: A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Expert opinion on drug safety, 2013 Sep .
- Riva A, "Deferasirox's toxicity", The Lancet, 2013 Jul .
- Kontoghiorghes GJ, "Turning a blind eye to deferasirox's toxicity?", The Lancet, 2013 Apr .
- Kontoghiorghes GJ, "A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Taylor & Francis, 2013 Jan .
Related studies
Drugs with ingredients of deferasirox, their effectiveness, alternatives and more:
How the study uses the data?
The study uses data from the FDA. It is based on deferasirox. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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