Bruxism and drugs of ingredients of divalproex sodium - a phase IV clinical study of FDA data
Bruxism is found among people who take drugs with ingredients of divalproex sodium, especially for people who are female, 60+ old , have been taking the drugs for 1 - 6 months. This phase IV clinical study is created by eHealthMe based on reports of 62,415 people who have side effects when taking drugs with ingredients of divalproex sodium from the FDA, and is updated regularly.
Drug(s) considered in the study (i.e. both brand name and generic drugs): Depakote, Depakote cp, Depakote er, Divalproex, Divalproex sodium, Epival.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
62,415 people reported to have side effects when taking drugs with ingredients of divalproex sodium.
Among them, 63 people (0.1%) have Bruxism
What is Bruxism?
Bruxism (habitual grinding of the teeth, typically during sleep) is found to be associated with 1,464 drugs and 892 conditions by eHealthMe.
Number of reports submitted per year:
Time on drugs with ingredients of divalproex sodium when people have Bruxism *:
- < 1 month: 30 %
- 1 - 6 months: 60 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 10 %
- 10+ years: 0.0 %
Gender of people who have Bruxism when taking drugs with ingredients of divalproex sodium *:
- female: 66.1 %
- male: 33.9 %
Age of people who have Bruxism when taking drugs with ingredients of divalproex sodium *:
- 0-1: 0.0 %
- 2-9: 4.26 %
- 10-19: 6.38 %
- 20-29: 8.51 %
- 30-39: 14.89 %
- 40-49: 19.15 %
- 50-59: 14.89 %
- 60+: 31.91 %
Conditions people have *:
- Depression: 8 people, 12.70%
- Insomnia (sleeplessness): 8 people, 12.70%
- Sleep Disorder: 7 people, 11.11%
- Hallucination, Visual (seeing things that aren't there): 6 people, 9.52%
- Schizoaffective Disorder (a mental disorder characterized by disordered thought): 6 people, 9.52%
- Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 5 people, 7.94%
- Hallucination, Auditory (perceiving sounds without auditory stimulus): 5 people, 7.94%
- Parkinsonian Rest Tremor: 5 people, 7.94%
- High Blood Pressure: 4 people, 6.35%
- Stress And Anxiety: 4 people, 6.35%
Other drugs people take *:
- Zyprexa: 15 people, 23.81%
- Haldol: 13 people, 20.63%
- Ativan: 11 people, 17.46%
- Klonopin: 11 people, 17.46%
- Abilify: 10 people, 15.87%
- Benadryl: 9 people, 14.29%
- Risperdal: 9 people, 14.29%
- Seroquel: 8 people, 12.70%
- Xanax: 7 people, 11.11%
- Zofran: 7 people, 11.11%
Other side effects people have besides Bruxism *:
- Abnormal Behavior: 15 people, 23.81%
- Pain: 14 people, 22.22%
- Tremor (trembling or shaking movements in one or more parts of your body): 14 people, 22.22%
- Suicidal Ideation: 13 people, 20.63%
- Aggression: 13 people, 20.63%
- Weight Increased: 12 people, 19.05%
- Weight Decreased: 12 people, 19.05%
- Hyperhidrosis (abnormally increased sweating): 12 people, 19.05%
- Dyskinesia (abnormality or impairment of voluntary movement): 11 people, 17.46%
- Head Injury: 11 people, 17.46%
* Approximation only. Some reports may have incomplete information.
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Drugs with ingredients of divalproex sodium, their effectiveness, alternatives and more:
How the study uses the data?
The study uses data from the FDA. It is based on divalproex sodium. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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