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Anal fistula and drugs of ingredients of docusate (a real world drug study)


Summary:

Anal fistula is found among people who take drugs with ingredients of docusate , especially for people who are male, 60+ old , have been taking the drugs for 6 - 12 months. This phase IV clinical study is created by eHealthMe based on reports of 90,369 people who have side effects when taking drugs with ingredients of docusate from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Colace.

On Aug, 07, 2026

90,369 people reported to have side effects when taking drugs with ingredients of docusate .
Among them, 32 people (0.04%) have Anal fistula

What is Anal fistula?

Anal fistula is found to be associated with 473 drugs and 637 conditions by eHealthMe. Check the latest studies of Anal fistula.

Number of reports submitted per year:

Could drugs with ingredients of docusate cause Anal fistula?

Time on drugs with ingredients of docusate when people have Anal fistula *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Anal fistula when taking drugs with ingredients of docusate *:

  • female: 48.39 %
  • male: 51.61 %

Age of people who have Anal fistula when taking drugs with ingredients of docusate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.7 %
  • 20-29: 3.7 %
  • 30-39: 11.11 %
  • 40-49: 14.81 %
  • 50-59: 18.52 %
  • 60+: 48.15 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 11 people, 34.38%
  2. Psoriasis (immune-mediated disease that affects the skin): 5 people, 15.62%
  3. Pain: 5 people, 15.62%
  4. Joint Pain: 4 people, 12.50%
  5. Hyperglycemia (high blood sugar): 4 people, 12.50%
  6. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 12.50%
  7. Nausea (feeling of having an urge to vomit): 4 people, 12.50%
  8. Gout (uric acid crystals building up in the body): 4 people, 12.50%
  9. Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 4 people, 12.50%
  10. Diabetes: 4 people, 12.50%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Humira: 10 people, 31.25%
  2. Valium: 7 people, 21.88%
  3. Metformin: 7 people, 21.88%
  4. Pantoprazole: 6 people, 18.75%
  5. Gliclazide: 6 people, 18.75%
  6. Ambien: 5 people, 15.62%
  7. Vitamin D: 5 people, 15.62%
  8. Flomax: 5 people, 15.62%
  9. Methotrexate: 5 people, 15.62%
  10. Ondansetron: 5 people, 15.62%

Other side effects people have besides Anal fistula *:

You may use this to check any potential undetected side effects.

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 28.12%
  2. Anorectal Abscess: 9 people, 28.12%
  3. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 6 people, 18.75%
  4. Drug Ineffective: 6 people, 18.75%
  5. Ocular Hyperaemia (an abnormally large amount of blood in eye): 5 people, 15.62%
  6. Febrile Neutropenia (fever with reduced white blood cells): 5 people, 15.62%
  7. Perirectal Abscess: 5 people, 15.62%
  8. Nausea (feeling of having an urge to vomit): 5 people, 15.62%
  9. Psoriasis (immune-mediated disease that affects the skin): 5 people, 15.62%
  10. Body Height Decreased: 5 people, 15.62%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of docusate , their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on docusate . All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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