Hyperthyroidism and drugs of ingredients of gabapentin (a real world drug study)


Summary:

Hyperthyroidism is found among people who take drugs with ingredients of gabapentin, especially for people who are female, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 415,239 people who have side effects when taking drugs with ingredients of gabapentin from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Gabapentin, Gralise, Neurontin.


On Nov, 23, 2025

415,239 people reported to have side effects when taking drugs with ingredients of gabapentin.
Among them, 275 people (0.07%) have Hyperthyroidism


What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,044 drugs and 1,417 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.

Number of reports submitted per year:

Could drugs with ingredients of gabapentin cause Hyperthyroidism?

Time on drugs with ingredients of gabapentin when people have Hyperthyroidism *:

  • < 1 month: 53.85 %
  • 1 - 6 months: 23.08 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 15.38 %
  • 5 - 10 years: 7.69 %
  • 10+ years: 0.0 %

Gender of people who have Hyperthyroidism when taking drugs with ingredients of gabapentin *:

  • female: 76.89 %
  • male: 23.11 %

Age of people who have Hyperthyroidism when taking drugs with ingredients of gabapentin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.97 %
  • 20-29: 6.4 %
  • 30-39: 11.82 %
  • 40-49: 23.15 %
  • 50-59: 21.67 %
  • 60+: 34.98 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. High Blood Pressure: 32 people, 11.64%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 32 people, 11.64%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 31 people, 11.27%
  4. Depression: 29 people, 10.55%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 25 people, 9.09%
  6. Stress And Anxiety: 24 people, 8.73%
  7. Nausea (feeling of having an urge to vomit): 23 people, 8.36%
  8. Insomnia (sleeplessness): 20 people, 7.27%
  9. Sleep Disorder: 19 people, 6.91%
  10. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 16 people, 5.82%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Miralax: 31 people, 11.27%
  2. Nexium: 29 people, 10.55%
  3. Lyrica: 28 people, 10.18%
  4. Vitamin D3: 27 people, 9.82%
  5. Xyrem: 27 people, 9.82%
  6. Percocet: 26 people, 9.45%
  7. Synthroid: 26 people, 9.45%
  8. Acetaminophen: 25 people, 9.09%
  9. Xanax: 24 people, 8.73%
  10. Prilosec: 24 people, 8.73%

Other side effects people have besides Hyperthyroidism *:

You may use this to check any potential undetected side effects.

  1. Fatigue (feeling of tiredness): 56 people, 20.36%
  2. Headache (pain in head): 50 people, 18.18%
  3. Dyspnea (difficult or laboured breathing): 49 people, 17.82%
  4. High Blood Pressure: 46 people, 16.73%
  5. Stress And Anxiety: 45 people, 16.36%
  6. Dizziness: 42 people, 15.27%
  7. Back Pain: 40 people, 14.55%
  8. Weakness: 39 people, 14.18%
  9. Insomnia (sleeplessness): 38 people, 13.82%
  10. Joint Pain: 38 people, 13.82%

* Approximation only. Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

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How the study uses the data?

The study uses data from the FDA. It is based on gabapentin. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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