Major depression and drugs of ingredients of gabapentin (a real world drug study)
Summary:
Major depression is found among people who take drugs with ingredients of gabapentin, especially for people who are female, 50-59 old , have been taking the drugs for 2 - 5 years. This phase IV clinical study is created by eHealthMe based on reports of 415,239 people who have side effects when taking drugs with ingredients of gabapentin from the FDA, and is updated regularly.
Drug(s) considered in the study (i.e. both brand name and generic drugs): Gabapentin, Gralise, Neurontin.
415,239 people reported to have side effects when taking drugs with ingredients of gabapentin.
Among them, 587 people (0.14%) have Major depression
What is Major depression?
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings) is found to be associated with 800 drugs and 1,477 conditions by eHealthMe. Check the latest studies of Major depression.
Number of reports submitted per year:

Time on drugs with ingredients of gabapentin when people have Major depression *:
- < 1 month: 10.0 %
- 1 - 6 months: 23.33 %
- 6 - 12 months: 13.33 %
- 1 - 2 years: 13.33 %
- 2 - 5 years: 23.33 %
- 5 - 10 years: 16.67 %
- 10+ years: 0.0 %
Gender of people who have Major depression when taking drugs with ingredients of gabapentin *:
- female: 57.81 %
- male: 42.19 %
Age of people who have Major depression when taking drugs with ingredients of gabapentin *:
- 0-1: 0.25 %
- 2-9: 0.0 %
- 10-19: 2.5 %
- 20-29: 9.0 %
- 30-39: 12.5 %
- 40-49: 22.5 %
- 50-59: 30.5 %
- 60+: 22.75 %
Conditions people have *:
You may use this to check any potential undetected conditions.
Other drugs people take *:
You may use this to check any potential interacting drugs.
Other side effects people have besides Major depression *:
You may use this to check any potential undetected side effects.
* Approximation only. Some reports may have incomplete information.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
Related studies
Drugs with ingredients of gabapentin, their effectiveness, alternatives and more:
How the study uses the data?
The study uses data from the FDA. It is based on gabapentin. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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