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Sinus node dysfunction and drugs of ingredients of gemfibrozil (a real world drug study)


Summary:

Sinus node dysfunction is found among people who take drugs with ingredients of gemfibrozil, especially for people who are male, 40-49 old , have been taking the drugs for 5 - 10 years. This phase IV clinical study is created by eHealthMe based on reports of 27,027 people who have side effects when taking drugs with ingredients of gemfibrozil from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Gemfibrozil, Lopid.

On Apr, 26, 2026

27,027 people reported to have side effects when taking drugs with ingredients of gemfibrozil.
Among them, 12 people (0.04%) have Sinus node dysfunction

What is Sinus node dysfunction?

Sinus node dysfunction (a group of abnormal heart rhythms) is found to be associated with 1,108 drugs and 843 conditions by eHealthMe. Check the latest studies of Sinus node dysfunction.

Number of reports submitted per year:

Could drugs with ingredients of gemfibrozil cause Sinus node dysfunction?

Time on drugs with ingredients of gemfibrozil when people have Sinus node dysfunction *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

Gender of people who have Sinus node dysfunction when taking drugs with ingredients of gemfibrozil *:

  • female: 8.33 %
  • male: 91.67 %

Age of people who have Sinus node dysfunction when taking drugs with ingredients of gemfibrozil *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 54.55 %
  • 50-59: 9.09 %
  • 60+: 36.36 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Stress And Anxiety: 6 people, 50.00%
  2. Nervousness: 6 people, 50.00%
  3. Insomnia (sleeplessness): 6 people, 50.00%
  4. Depression: 6 people, 50.00%
  5. Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 2 people, 16.67%
  6. Diabetes: 1 person, 8.33%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 8.33%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Effexor: 8 people, 66.67%
  2. Coumadin: 8 people, 66.67%
  3. Lopressor: 7 people, 58.33%
  4. Xanax: 7 people, 58.33%
  5. Lortab: 7 people, 58.33%
  6. Avandia: 7 people, 58.33%
  7. Keflex: 7 people, 58.33%
  8. Isordil: 6 people, 50.00%
  9. Avandamet: 6 people, 50.00%
  10. Lantus: 6 people, 50.00%

Other side effects people have besides Sinus node dysfunction *:

You may use this to check any potential undetected side effects.

  1. Type 2 Diabetes: 7 people, 58.33%
  2. Death: 7 people, 58.33%
  3. Diabetes: 6 people, 50.00%
  4. Cardiac Disorder: 6 people, 50.00%
  5. Circulatory Collapse: 6 people, 50.00%
  6. Arthropathy: 5 people, 41.67%
  7. Bradycardia (abnormally slow heart action): 4 people, 33.33%
  8. Arrhythmias (irregular heartbeat): 3 people, 25.00%
  9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 25.00%
  10. Cardiac Failure Congestive: 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of gemfibrozil, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on gemfibrozil. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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