Alloimmunisation and drugs of ingredients of hydroxyurea (a real world drug study)


Summary:

Alloimmunisation is reported only by a few people who take drugs with ingredients of hydroxyurea. This phase IV clinical study analyzes 25,825 people who have side effects while taking drugs with ingredients of hydroxyurea from the the FDA. Among them, 3 have Alloimmunisation. Find out below who they are, when they have Alloimmunisation and more.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Droxia, Hydrea, Hydroxyurea, Siklos, Xromi.


On Jun, 18, 2026

25,825 people reported to have side effects when taking drugs with ingredients of hydroxyurea.
Among them, 3 people (0.01%) have Alloimmunisation


What is Alloimmunisation?

Alloimmunisation (alloimmunity is an immune response to foreign antigens (alloantigens) from members of the same species) is found to be associated with 4 drugs and 30 conditions by eHealthMe. Check the latest studies of Alloimmunisation.

Number of reports submitted per year:

Could drugs with ingredients of hydroxyurea cause Alloimmunisation?

Time on drugs with ingredients of hydroxyurea when people have Alloimmunisation *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Alloimmunisation when taking drugs with ingredients of hydroxyurea *:

  • female: 33.33 %
  • male: 66.67 %

Age of people who have Alloimmunisation when taking drugs with ingredients of hydroxyurea *:

  • 0-1: 0.0 %
  • 2-9: 50 %
  • 10-19: 0.0 %
  • 20-29: 50 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 33.33%
  2. Pain: 1 person, 33.33%
  3. Iron Overload: 1 person, 33.33%
  4. High Blood Pressure: 1 person, 33.33%
  5. Birth Control: 1 person, 33.33%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Jadenu: 2 people, 66.67%
  2. Sprintec: 1 person, 33.33%
  3. Biotin: 1 person, 33.33%
  4. Busulfex: 1 person, 33.33%
  5. Cyclophosphamide: 1 person, 33.33%
  6. Cyclosporine: 1 person, 33.33%
  7. Endari: 1 person, 33.33%
  8. Exjade: 1 person, 33.33%
  9. Fluconazole: 1 person, 33.33%
  10. Folic Acid: 1 person, 33.33%

Other side effects people have besides Alloimmunisation *:

You may use this to check any potential undetected side effects.

  1. Haemoglobin Decreased: 3 people, 100.00%
  2. Gallstones (stone formation by bile component): 1 person, 33.33%
  3. Fever: 1 person, 33.33%
  4. Feeling Abnormal: 1 person, 33.33%
  5. Febrile Neutropenia (fever with reduced white blood cells): 1 person, 33.33%
  6. Eye Pain: 1 person, 33.33%
  7. Enterovirus Test Positive: 1 person, 33.33%
  8. Diarrhea: 1 person, 33.33%
  9. Dactylitis (dactylitis or sausage digit is inflammation of an entire digit (a finger or toe), and can be painful): 1 person, 33.33%
  10. Thrombocytopenia (decrease of platelets in blood): 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of hydroxyurea, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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