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Headache and drugs of ingredients of imipramine pamoate (a real world drug study)


Summary:

Headache is found among people who take drugs with ingredients of imipramine pamoate, especially for people who are female, 30-39 old , have been taking the drugs for 6 - 12 months. This phase IV clinical study is created by eHealthMe based on reports of 476 people who have side effects when taking drugs with ingredients of imipramine pamoate from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Imipramine pamoate, Tofranil-pm.

On Jun, 15, 2026

476 people reported to have side effects when taking drugs with ingredients of imipramine pamoate.
Among them, 19 people (3.99%) have Headache

What is Headache?

Headache (pain in head) is found to be associated with 3,745 drugs and 5,764 conditions by eHealthMe. Check the latest studies of Headache.

Number of reports submitted per year:

Could drugs with ingredients of imipramine pamoate cause Headache?

Time on drugs with ingredients of imipramine pamoate when people have Headache *:

  • < 1 month: 16.67 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 50.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Headache when taking drugs with ingredients of imipramine pamoate *:

  • female: 82.35 %
  • male: 17.65 %

Age of people who have Headache when taking drugs with ingredients of imipramine pamoate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 8.33 %
  • 30-39: 50.0 %
  • 40-49: 16.67 %
  • 50-59: 0.0 %
  • 60+: 25.0 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 21.05%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 15.79%
  3. Sleep Disorder: 2 people, 10.53%
  4. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 10.53%
  5. Migraine (headache): 2 people, 10.53%
  6. Pinworms: 1 person, 5.26%
  7. Nausea (feeling of having an urge to vomit): 1 person, 5.26%
  8. Muscle Spasms (muscle contraction): 1 person, 5.26%
  9. Incontinence (lack of moderation or self-control): 1 person, 5.26%
  10. Fungal Nail Infection: 1 person, 5.26%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Cymbalta: 5 people, 26.32%
  2. Lamictal: 3 people, 15.79%
  3. Xyrem: 3 people, 15.79%
  4. Pregabalin: 3 people, 15.79%
  5. Promethazine: 3 people, 15.79%
  6. Diclofenac: 2 people, 10.53%
  7. Glucosamine: 2 people, 10.53%
  8. Gilenya: 2 people, 10.53%
  9. Frova: 2 people, 10.53%
  10. Fluoxetine: 2 people, 10.53%

Other side effects people have besides Headache *:

You may use this to check any potential undetected side effects.

  1. Fall: 4 people, 21.05%
  2. Fever: 4 people, 21.05%
  3. Hospitalisation: 4 people, 21.05%
  4. Nausea (feeling of having an urge to vomit): 4 people, 21.05%
  5. Insomnia (sleeplessness): 3 people, 15.79%
  6. Dizziness: 3 people, 15.79%
  7. Stress And Anxiety: 3 people, 15.79%
  8. Hypersensitivity: 3 people, 15.79%
  9. Fatigue (feeling of tiredness): 3 people, 15.79%
  10. Gait Disturbance: 3 people, 15.79%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of imipramine pamoate, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on imipramine pamoate. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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