Anuria and drugs of ingredients of leflunomide (a real world drug study)


Summary:

Anuria is found among people who take drugs with ingredients of leflunomide, especially for people who are female, 60+ old , have been taking the drugs for 6 - 12 months. This phase IV clinical study is created by eHealthMe based on reports of 140,215 people who have side effects when taking drugs with ingredients of leflunomide from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Arava, Leflunomide.


On Jun, 06, 2026

140,215 people reported to have side effects when taking drugs with ingredients of leflunomide.
Among them, 36 people (0.03%) have Anuria


What is Anuria?

Anuria (failure of the kidneys to produce urine) is found to be associated with 867 drugs and 1,239 conditions by eHealthMe. Check the latest studies of Anuria.

Number of reports submitted per year:

Could drugs with ingredients of leflunomide cause Anuria?

Time on drugs with ingredients of leflunomide when people have Anuria *:

  • < 1 month: 25.0 %
  • 1 - 6 months: 37.5 %
  • 6 - 12 months: 37.5 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Anuria when taking drugs with ingredients of leflunomide *:

  • female: 60 %
  • male: 40 %

Age of people who have Anuria when taking drugs with ingredients of leflunomide *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6.67 %
  • 30-39: 0.0 %
  • 40-49: 23.33 %
  • 50-59: 10.0 %
  • 60+: 60.0 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Cardiac Sarcoidosis (an immune disorder): 5 people, 13.89%
  2. Type 2 Diabetes: 1 person, 2.78%
  3. Stress And Anxiety: 1 person, 2.78%
  4. Stable Angina (a constant chest pain): 1 person, 2.78%
  5. Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 1 person, 2.78%
  6. Hypersensitivity: 1 person, 2.78%
  7. High Blood Pressure: 1 person, 2.78%
  8. Hepatitis C: 1 person, 2.78%
  9. Gastric Ulcer (stomach ulcer): 1 person, 2.78%
  10. Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 2.78%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Prednisone: 12 people, 33.33%
  2. Methotrexate: 12 people, 33.33%
  3. Prednisolone: 8 people, 22.22%
  4. Humira: 5 people, 13.89%
  5. Lasix: 5 people, 13.89%
  6. Fentanyl: 4 people, 11.11%
  7. Famotidine: 4 people, 11.11%
  8. Remicade: 4 people, 11.11%
  9. Methadone Hydrochloride: 4 people, 11.11%
  10. Imuran: 3 people, 8.33%

Other side effects people have besides Anuria *:

You may use this to check any potential undetected side effects.

  1. Hypotension (abnormally low blood pressure): 16 people, 44.44%
  2. Acute Kidney Failure: 13 people, 36.11%
  3. Fever: 12 people, 33.33%
  4. Septic Shock (shock due to blood infection): 10 people, 27.78%
  5. Fatigue (feeling of tiredness): 10 people, 27.78%
  6. General Physical Health Deterioration (weak health status): 8 people, 22.22%
  7. Staphylococcal Infection (an infection with staphylococcus bacteria): 8 people, 22.22%
  8. Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 7 people, 19.44%
  9. Multi-Organ Failure (multisystem organ failure): 7 people, 19.44%
  10. Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 19.44%

* Approximation only. Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of leflunomide, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on leflunomide. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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