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Hypophysitis and drugs of ingredients of macitentan (a real world drug study)


Summary:

Hypophysitis is reported only by a few people who take drugs with ingredients of macitentan. This phase IV clinical study analyzes 75,003 people who have side effects while taking drugs with ingredients of macitentan from the the FDA. Among them, 4 have Hypophysitis. Find out below who they are, when they have Hypophysitis and more.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Macitentan, Opsumit.

On Jun, 23, 2026

75,003 people reported to have side effects when taking drugs with ingredients of macitentan.
Among them, 4 people (0.01%) have Hypophysitis

What is Hypophysitis?

Hypophysitis (inflammation of the pituitary gland) is found to be associated with 159 drugs and 172 conditions by eHealthMe. Check the latest studies of Hypophysitis.

Number of reports submitted per year:

Could drugs with ingredients of macitentan cause Hypophysitis?

Gender of people who have Hypophysitis when taking drugs with ingredients of macitentan *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Hypophysitis when taking drugs with ingredients of macitentan *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 66.67 %
  • 40-49: 33.33 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 100.00%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Flolan: 2 people, 50.00%
  2. Adempas: 1 person, 25.00%

Other side effects people have besides Hypophysitis *:

You may use this to check any potential undetected side effects.

  1. Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 4 people, 100.00%
  2. Pituitary Enlargement: 2 people, 50.00%
  3. Joint Pain: 2 people, 50.00%
  4. Hypotension (abnormally low blood pressure): 2 people, 50.00%
  5. Gastroenteritis (inflammation of stomach and intestine): 2 people, 50.00%
  6. Fever: 2 people, 50.00%
  7. Dehydration (dryness resulting from the removal of water): 2 people, 50.00%
  8. Altered State Of Consciousness (altered state of mind): 2 people, 50.00%
  9. Blood Corticotrophin Decreased: 1 person, 25.00%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of macitentan, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on macitentan. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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