Liver function test abnormal and drugs of ingredients of memantine (a real world drug study)


Summary:

Liver function test abnormal is found among people who take drugs with ingredients of memantine, especially for people who are male, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 10,128 people who have side effects when taking drugs with ingredients of memantine from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Memantine.


On Apr, 20, 2026

10,128 people reported to have side effects when taking drugs with ingredients of memantine.
Among them, 42 people (0.41%) have Liver function test abnormal


What is Liver function test abnormal?

Liver function test abnormal is found to be associated with 1,513 drugs and 1,959 conditions by eHealthMe. Check the latest studies of Liver function test abnormal.

Number of reports submitted per year:

Could drugs with ingredients of memantine cause Liver function test abnormal?

Time on drugs with ingredients of memantine when people have Liver function test abnormal *:

  • < 1 month: 50.0 %
  • 1 - 6 months: 16.67 %
  • 6 - 12 months: 16.67 %
  • 1 - 2 years: 16.67 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Liver function test abnormal when taking drugs with ingredients of memantine *:

  • female: 39.47 %
  • male: 60.53 %

Age of people who have Liver function test abnormal when taking drugs with ingredients of memantine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. High Blood Pressure: 2 people, 4.76%
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 2 people, 4.76%
  3. Pick's Disease (progressive dementia): 2 people, 4.76%
  4. Pain: 2 people, 4.76%
  5. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 2 people, 4.76%
  6. Memory Loss: 2 people, 4.76%
  7. Depression: 2 people, 4.76%
  8. Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 2.38%
  9. Breast Cancer: 1 person, 2.38%
  10. Bronchopneumopathy: 1 person, 2.38%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Metformin: 15 people, 35.71%
  2. Lorazepam: 13 people, 30.95%
  3. Apixaban: 10 people, 23.81%
  4. Sertraline: 10 people, 23.81%
  5. Omeprazole: 10 people, 23.81%
  6. Ferrous Fumarate: 9 people, 21.43%
  7. Nitroglycerin: 9 people, 21.43%
  8. Aripiprazole: 9 people, 21.43%
  9. Olanzapine: 9 people, 21.43%
  10. Latanoprost: 9 people, 21.43%

Other side effects people have besides Liver function test abnormal *:

You may use this to check any potential undetected side effects.

  1. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 10 people, 23.81%
  2. Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 9 people, 21.43%
  3. Hepatotoxicity (chemical-driven liver damage): 4 people, 9.52%
  4. Fatigue (feeling of tiredness): 3 people, 7.14%
  5. Drug Ineffective: 2 people, 4.76%
  6. Haemoglobin Decreased: 1 person, 2.38%
  7. Haematoma (collection of blood outside the blood vessels): 1 person, 2.38%
  8. General Physical Health Deterioration (weak health status): 1 person, 2.38%
  9. Gamma-Glutamyltransferase Increased: 1 person, 2.38%
  10. Food Aversion (we reject certain foods for a reason): 1 person, 2.38%

* Approximation only. Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

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How the study uses the data?

The study uses data from the FDA. It is based on memantine. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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