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Executive dysfunction and drugs of ingredients of modafinil (a real world drug study)


Summary:

Executive dysfunction is found among people who take drugs with ingredients of modafinil, especially for people who are female, 30-39 old . This phase IV clinical study is created by eHealthMe based on reports of 42,385 people who have side effects when taking drugs with ingredients of modafinil from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Modafinil, Provigil.

On Jun, 18, 2026

42,385 people reported to have side effects when taking drugs with ingredients of modafinil.
Among them, 14 people (0.03%) have Executive dysfunction

What is Executive dysfunction?

Executive dysfunction is found to be associated with 47 drugs and 131 conditions by eHealthMe. Check the latest studies of Executive dysfunction.

Number of reports submitted per year:

Could drugs with ingredients of modafinil cause Executive dysfunction?

Gender of people who have Executive dysfunction when taking drugs with ingredients of modafinil *:

  • female: 92.86 %
  • male: 7.14 %

Age of people who have Executive dysfunction when taking drugs with ingredients of modafinil *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.14 %
  • 30-39: 78.57 %
  • 40-49: 7.14 %
  • 50-59: 7.14 %
  • 60+: 0.0 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 85.71%
  2. Stress And Anxiety: 11 people, 78.57%
  3. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 14.29%
  4. Anaemia (lack of blood): 2 people, 14.29%
  5. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 7.14%
  6. Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 7.14%
  7. Pathogen Resistance: 1 person, 7.14%
  8. Muscle Aches (muscle pain): 1 person, 7.14%
  9. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 7.14%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Escitalopram: 12 people, 85.71%
  2. Lioresal: 8 people, 57.14%
  3. Baclofen: 4 people, 28.57%
  4. Gilenya: 2 people, 14.29%
  5. Zoloft: 1 person, 7.14%
  6. Hydrocodone Bitartrate And Acetaminophen: 1 person, 7.14%
  7. Cephalexin: 1 person, 7.14%
  8. Clonazepam: 1 person, 7.14%
  9. Cogentin: 1 person, 7.14%
  10. Coumadin: 1 person, 7.14%

Other side effects people have besides Executive dysfunction *:

You may use this to check any potential undetected side effects.

  1. Irritability: 13 people, 92.86%
  2. Memory Loss: 12 people, 85.71%
  3. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 12 people, 85.71%
  4. Nausea (feeling of having an urge to vomit): 12 people, 85.71%
  5. Confusion: 12 people, 85.71%
  6. Headache (pain in head): 12 people, 85.71%
  7. Speech Impairment (Adult) (inability to speak (adult)): 12 people, 85.71%
  8. Hoarseness Or Changing Voice: 11 people, 78.57%
  9. Loss Of Consciousness: 11 people, 78.57%
  10. Weakness: 11 people, 78.57%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related publications that referenced our studies

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Drugs with ingredients of modafinil, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on modafinil. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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