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Pain and drugs of ingredients of pantethine (a real world drug study)


Summary:

Pain is found among people who take drugs with ingredients of pantethine, especially for people who are male, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 1,932 people who have side effects when taking drugs with ingredients of pantethine from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Bis-pantothenamidoethyl disulfide, D-bis-(n-pantothenyl-b-aminoethyl)-disulfide, D-pantethine, Pantethine, Pantethine octahydrate, Pantetina, Pantomin, Pantosin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 03, 2026

1,932 people reported to have side effects when taking drugs with ingredients of pantethine.
Among them, 19 people (0.98%) have Pain

What is Pain?

Pain is found to be associated with 3,808 drugs and 5,872 conditions by eHealthMe. Check the latest studies of Pain.

Number of reports submitted per year:

Could drugs with ingredients of pantethine cause Pain?

Time on drugs with ingredients of pantethine when people have Pain *:

  • < 1 month: 33.33 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 33.33 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Pain when taking drugs with ingredients of pantethine *:

  • female: 43.75 %
  • male: 56.25 %

Age of people who have Pain when taking drugs with ingredients of pantethine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 21.43 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 21.43 %
  • 60+: 57.14 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Multiple Myeloma (cancer of the plasma cells): 7 people, 36.84%
  2. Insomnia (sleeplessness): 5 people, 26.32%
  3. Constipation: 4 people, 21.05%
  4. Depression: 4 people, 21.05%
  5. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 3 people, 15.79%
  6. High Blood Pressure: 3 people, 15.79%
  7. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 15.79%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 15.79%
  9. Anaemia (lack of blood): 2 people, 10.53%
  10. Cancer Pain: 2 people, 10.53%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Sulfamethoxazole And Trimethoprim: 6 people, 31.58%
  2. Acyclovir: 3 people, 15.79%
  3. Amlodipine Besylate: 3 people, 15.79%
  4. Farydak: 3 people, 15.79%
  5. Fentanyl: 3 people, 15.79%
  6. Fluvastatin Sodium: 3 people, 15.79%
  7. Humira: 3 people, 15.79%
  8. Itraconazole: 3 people, 15.79%
  9. Lamivudine: 3 people, 15.79%
  10. Lansoprazole: 3 people, 15.79%

Other side effects people have besides Pain *:

You may use this to check any potential undetected side effects.

  1. Fever: 7 people, 36.84%
  2. Thrombocytopenia (decrease of platelets in blood): 7 people, 36.84%
  3. Dyspnea (difficult or laboured breathing): 6 people, 31.58%
  4. Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 4 people, 21.05%
  5. Dehydration (dryness resulting from the removal of water): 4 people, 21.05%
  6. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 21.05%
  7. Malignant Neoplasm Progression (cancer tumour came back): 4 people, 21.05%
  8. C-Reactive Protein Increased: 3 people, 15.79%
  9. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 15.79%
  10. Cough: 3 people, 15.79%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of pantethine, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on pantethine. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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