Malaise and drugs of ingredients of risdiplam (a real world drug study)


Summary:

Malaise is found among people who take drugs with ingredients of risdiplam, especially for people who are male, 2-9 old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 2,765 people who have side effects when taking drugs with ingredients of risdiplam from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Evrysdi.


On Jul, 31, 2026

2,765 people reported to have side effects when taking drugs with ingredients of risdiplam.
Among them, 37 people (1.34%) have Malaise


What is Malaise?

Malaise (a feeling of general discomfort or uneasiness) is found to be associated with 3,497 drugs and 5,122 conditions by eHealthMe. Check the latest studies of Malaise.

Number of reports submitted per year:

Could drugs with ingredients of risdiplam cause Malaise?

Time on drugs with ingredients of risdiplam when people have Malaise *:

  • < 1 month: 83.33 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 16.67 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Malaise when taking drugs with ingredients of risdiplam *:

  • female: 47.06 %
  • male: 52.94 %

Age of people who have Malaise when taking drugs with ingredients of risdiplam *:

  • 0-1: 0.0 %
  • 2-9: 35 %
  • 10-19: 25 %
  • 20-29: 15 %
  • 30-39: 10 %
  • 40-49: 10 %
  • 50-59: 5 %
  • 60+: 0.0 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Spinal Muscular Atrophy (wasting of spinal muscles): 33 people, 89.19%
  2. Pneumonia: 4 people, 10.81%
  3. Obstruction: 3 people, 8.11%
  4. Insomnia (sleeplessness): 1 person, 2.70%
  5. Hypokalemia (low potassium): 1 person, 2.70%
  6. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 2.70%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Spinraza: 8 people, 21.62%
  2. Albuterol: 3 people, 8.11%
  3. Zoloft: 2 people, 5.41%
  4. Morphine: 2 people, 5.41%
  5. Zyrtec: 1 person, 2.70%
  6. Vitamin D: 1 person, 2.70%
  7. Rogaine: 1 person, 2.70%
  8. Potassium: 1 person, 2.70%
  9. Morphine Sulfate: 1 person, 2.70%
  10. Melatonin: 1 person, 2.70%

Other side effects people have besides Malaise *:

You may use this to check any potential undetected side effects.

  1. Weakness: 7 people, 18.92%
  2. Pneumonia: 5 people, 13.51%
  3. Fever: 4 people, 10.81%
  4. Nausea And Vomiting: 4 people, 10.81%
  5. The Flu (the flu is caused by an influenza virus): 4 people, 10.81%
  6. Back Pain: 4 people, 10.81%
  7. Drug Hypersensitivity: 4 people, 10.81%
  8. Diarrhea: 3 people, 8.11%
  9. Fatigue (feeling of tiredness): 3 people, 8.11%
  10. Dizziness: 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of risdiplam, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on risdiplam. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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