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Icterus and drugs of ingredients of same (a real world drug study)


Summary:

Icterus is found among people who take drugs with ingredients of same, especially for people who are male, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 1,178 people who have side effects when taking drugs with ingredients of same from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Ademetionine, Adenosylmethionine, S-adenosyl-l-methionine, Sam-e, Same, Sammy.

On Jun, 18, 2026

1,178 people reported to have side effects when taking drugs with ingredients of same.
Among them, 13 people (1.1%) have Icterus

What is Icterus?

Icterus (yellowish pigmentation of the skin) is found to be associated with 1,968 drugs and 3,030 conditions by eHealthMe. Check the latest studies of Icterus.

Number of reports submitted per year:

Could drugs with ingredients of same cause Icterus?

Time on drugs with ingredients of same when people have Icterus *:

  • < 1 month: 70 %
  • 1 - 6 months: 10 %
  • 6 - 12 months: 20 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Icterus when taking drugs with ingredients of same *:

  • female: 38.46 %
  • male: 61.54 %

Age of people who have Icterus when taking drugs with ingredients of same *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 23.08 %
  • 50-59: 7.69 %
  • 60+: 69.23 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Systemic Candida (whole body fungal infection): 4 people, 30.77%
  2. Rashes (redness): 4 people, 30.77%
  3. Pneumonia: 4 people, 30.77%
  4. Hepatic Function Abnormal: 4 people, 30.77%
  5. Coughing Up Blood: 4 people, 30.77%
  6. Candidiasis (candidiasis or thrush is a fungal infection): 4 people, 30.77%
  7. Rickets (softening of bones): 2 people, 15.38%
  8. Oestrogen Deficiency (lack of estrogens): 2 people, 15.38%
  9. Immune System Disorder: 2 people, 15.38%
  10. Hepatic Neoplasm Malignant (liver cancer): 2 people, 15.38%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Aminophylline: 4 people, 30.77%
  2. Sulfamethoxazole: 4 people, 30.77%
  3. Itraconazole: 4 people, 30.77%
  4. Loratadine: 4 people, 30.77%
  5. Methylprednisolone: 4 people, 30.77%
  6. Caspofungin Acetate: 4 people, 30.77%
  7. Fluconazole: 4 people, 30.77%
  8. Amphotericin B: 4 people, 30.77%
  9. Tinospora Cordifolia: 2 people, 15.38%
  10. Oil Of Oregano: 2 people, 15.38%

Other side effects people have besides Icterus *:

You may use this to check any potential undetected side effects.

  1. Hepatic Enzyme Increased: 6 people, 46.15%
  2. Fatigue (feeling of tiredness): 5 people, 38.46%
  3. Acute Monocytic Leukaemia (a type of blood cancer): 4 people, 30.77%
  4. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 30.77%
  5. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 4 people, 30.77%
  6. Lung Infection: 4 people, 30.77%
  7. Ascites (accumulation of fluid in the abdominal cavity): 4 people, 30.77%
  8. Weakness: 3 people, 23.08%
  9. Fungus Culture Positive: 3 people, 23.08%
  10. Nausea (feeling of having an urge to vomit): 3 people, 23.08%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of same, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on same. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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