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Sciatic nerve dysfunction and drugs of ingredients of sofosbuvir (a real world drug study)


Summary:

Sciatic nerve dysfunction is found among people who take drugs with ingredients of sofosbuvir, especially for people who are female, 50-59 old , have been taking the drugs for 1 - 6 months. This phase IV clinical study is created by eHealthMe based on reports of 21,826 people who have side effects when taking drugs with ingredients of sofosbuvir from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Sofosbuvir, Sovaldi.

On Jun, 22, 2026

21,826 people reported to have side effects when taking drugs with ingredients of sofosbuvir.
Among them, 10 people (0.05%) have Sciatic nerve dysfunction

What is Sciatic nerve dysfunction?

Sciatic nerve dysfunction (a condition in which the sciatic nerve conducts impulses abnormally) is found to be associated with 1,826 drugs and 1,461 conditions by eHealthMe. Check the latest studies of Sciatic nerve dysfunction.

Number of reports submitted per year:

Could drugs with ingredients of sofosbuvir cause Sciatic nerve dysfunction?

Time on drugs with ingredients of sofosbuvir when people have Sciatic nerve dysfunction *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Sciatic nerve dysfunction when taking drugs with ingredients of sofosbuvir *:

  • female: 70 %
  • male: 30 %

Age of people who have Sciatic nerve dysfunction when taking drugs with ingredients of sofosbuvir *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 71.43 %
  • 60+: 28.57 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Hepatitis C: 4 people, 40.00%
  2. Stress And Anxiety: 2 people, 20.00%
  3. Oedema Peripheral (superficial swelling): 2 people, 20.00%
  4. High Blood Pressure: 2 people, 20.00%
  5. High Blood Cholesterol: 2 people, 20.00%
  6. Anaemia (lack of blood): 2 people, 20.00%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Plavix: 2 people, 20.00%
  2. Atacand: 2 people, 20.00%
  3. Aldactone: 2 people, 20.00%
  4. Suboxone: 1 person, 10.00%
  5. Rebetol: 1 person, 10.00%
  6. Pegintron: 1 person, 10.00%
  7. Omeprazole: 1 person, 10.00%
  8. Lansoprazole: 1 person, 10.00%
  9. Daklinza: 1 person, 10.00%
  10. Cymbalta: 1 person, 10.00%

Other side effects people have besides Sciatic nerve dysfunction *:

You may use this to check any potential undetected side effects.

  1. Fatigue (feeling of tiredness): 4 people, 40.00%
  2. Nausea (feeling of having an urge to vomit): 3 people, 30.00%
  3. Weight Decreased: 2 people, 20.00%
  4. Tendonitis (a condition that causes pain and swelling of tendons): 2 people, 20.00%
  5. Weakness: 2 people, 20.00%
  6. Genotype Drug Resistance Test Positive: 2 people, 20.00%
  7. Pain In Extremity: 2 people, 20.00%
  8. Drug Ineffective: 2 people, 20.00%
  9. Gait Disturbance: 1 person, 10.00%
  10. Flank Pain (a distressing sensation experienced around the lower back and the upper abdomen): 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of sofosbuvir, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on sofosbuvir. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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