Ventricular dysfunction and drugs of ingredients of tacrolimus (a real world drug study)


Summary:

Ventricular dysfunction is found among people who take drugs with ingredients of tacrolimus, especially for people who are male, 40-49 old , have been taking the drugs for 1 - 6 months. This phase IV clinical study is created by eHealthMe based on reports of 164,313 people who have side effects when taking drugs with ingredients of tacrolimus from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Astagraf xl, Envarsus xr, Prograf, Protopic, Tacrolimus.


On Jun, 20, 2026

164,313 people reported to have side effects when taking drugs with ingredients of tacrolimus.
Among them, 26 people (0.02%) have Ventricular dysfunction


What is Ventricular dysfunction?

Ventricular dysfunction (heart dysfunction) is found to be associated with 459 drugs and 551 conditions by eHealthMe. Check the latest studies of Ventricular dysfunction.

Number of reports submitted per year:

Could drugs with ingredients of tacrolimus cause Ventricular dysfunction?

Time on drugs with ingredients of tacrolimus when people have Ventricular dysfunction *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 50 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Ventricular dysfunction when taking drugs with ingredients of tacrolimus *:

  • female: 23.08 %
  • male: 76.92 %

Age of people who have Ventricular dysfunction when taking drugs with ingredients of tacrolimus *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 7.69 %
  • 20-29: 11.54 %
  • 30-39: 3.85 %
  • 40-49: 42.31 %
  • 50-59: 11.54 %
  • 60+: 23.08 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 23.08%
  2. Serositis (inflammation of the serous tissues of the body): 2 people, 7.69%
  3. Hypertriglyceridaemia (excess of triglycerides in the blood): 2 people, 7.69%
  4. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 7.69%
  5. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 7.69%
  6. Depression: 2 people, 7.69%
  7. Uveitis (inflammation of the uvea): 1 person, 3.85%
  8. Urination - Excessive Volume: 1 person, 3.85%
  9. Transplant Rejection (a transplant material is not worked): 1 person, 3.85%
  10. Poor Quality Sleep: 1 person, 3.85%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Enbrel: 6 people, 23.08%
  2. Mycophenolate Mofetil: 6 people, 23.08%
  3. Bactrim: 5 people, 19.23%
  4. Aspirin: 4 people, 15.38%
  5. Nystatin: 4 people, 15.38%
  6. Prednisone: 4 people, 15.38%
  7. Furosemide: 3 people, 11.54%
  8. Enalapril Maleate: 3 people, 11.54%
  9. Lasix: 3 people, 11.54%
  10. Etoposide: 3 people, 11.54%

Other side effects people have besides Ventricular dysfunction *:

You may use this to check any potential undetected side effects.

  1. Dyspnea (difficult or laboured breathing): 12 people, 46.15%
  2. Arrhythmias (irregular heartbeat): 9 people, 34.62%
  3. Cardiac Failure Congestive: 8 people, 30.77%
  4. Weakness: 7 people, 26.92%
  5. Infusion Related Reaction: 6 people, 23.08%
  6. Vertebral Foraminal Stenosis (narrowing of the intervertebral foramen): 6 people, 23.08%
  7. Impaired Healing: 6 people, 23.08%
  8. Hypoaesthesia (reduced sense of touch or sensation): 6 people, 23.08%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 23.08%
  10. Gait Disturbance: 6 people, 23.08%

* Approximation only. Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

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How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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