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Pneumothorax and drugs of ingredients of thiotepa (a real world drug study)


Summary:

Pneumothorax is found among people who take drugs with ingredients of thiotepa, especially for people who are female, 20-29 old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 8,344 people who have side effects when taking drugs with ingredients of thiotepa from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Tepadina, Thioplex, Thiotepa.

eHealthMe: drug outcomes in the real world

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On Aug, 23, 2026

8,344 people reported to have side effects when taking drugs with ingredients of thiotepa.
Among them, 19 people (0.23%) have Pneumothorax

What is Pneumothorax?

Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung) is found to be associated with 1,234 drugs and 1,346 conditions by eHealthMe. Check the latest studies of Pneumothorax.

Number of reports submitted per year:

Could drugs with ingredients of thiotepa cause Pneumothorax?

Time on drugs with ingredients of thiotepa when people have Pneumothorax *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Pneumothorax when taking drugs with ingredients of thiotepa *:

  • female: 71.43 %
  • male: 28.57 %

Age of people who have Pneumothorax when taking drugs with ingredients of thiotepa *:

  • 0-1: 0.0 %
  • 2-9: 44.44 %
  • 10-19: 11.11 %
  • 20-29: 44.44 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Medulloblastoma (a fast-growing, high-grade tumour that always begins in the cerebellum): 5 people, 26.32%
  2. Fever: 3 people, 15.79%
  3. Recurrent Cancer (repeated cancer): 1 person, 5.26%
  4. Neuroblastoma (a cancer that forms in your nerve tissue): 1 person, 5.26%
  5. Nausea (feeling of having an urge to vomit): 1 person, 5.26%
  6. Immunodeficiency Disorders: 1 person, 5.26%
  7. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 5.26%
  8. Depression: 1 person, 5.26%
  9. Constipation: 1 person, 5.26%
  10. Clostridium Difficile Colitis (inflammation of colon by clostridium difficile bacteria infection): 1 person, 5.26%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Cyclophosphamide: 8 people, 42.11%
  2. Etoposide: 7 people, 36.84%
  3. Carboplatin: 6 people, 31.58%
  4. Cellcept: 6 people, 31.58%
  5. Ciclosporin: 6 people, 31.58%
  6. Melphalan: 3 people, 15.79%
  7. Cyclosporine: 2 people, 10.53%
  8. Vancomycin: 1 person, 5.26%
  9. Ursodiol: 1 person, 5.26%
  10. Busulfan: 1 person, 5.26%

Other side effects people have besides Pneumothorax *:

You may use this to check any potential undetected side effects.

  1. Pericardial Effusion (fluid around the heart): 9 people, 47.37%
  2. Mucosal Inflammation (infection of mucous membrane): 9 people, 47.37%
  3. Weight Increased: 8 people, 42.11%
  4. Nausea (feeling of having an urge to vomit): 8 people, 42.11%
  5. Sepsis (a severe blood infection that can lead to organ failure and death): 8 people, 42.11%
  6. Pneumomediastinum (air is present in the mediastinum): 7 people, 36.84%
  7. Myocarditis (inflammation of heart muscle myocardium): 7 people, 36.84%
  8. Hepatomegaly (abnormal enlargement of the liver): 7 people, 36.84%
  9. Pelvic Fluid Collection: 7 people, 36.84%
  10. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 7 people, 36.84%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of thiotepa, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on thiotepa. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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