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Mouth ulcers and drugs of ingredients of vitamin k (a real world drug study)


Summary:

Mouth ulcers is found among people who take drugs with ingredients of vitamin k, especially for people who are female, 60+ old , have been taking the drugs for < 1 month. This phase IV clinical study is created by eHealthMe based on reports of 7,499 people who have side effects when taking drugs with ingredients of vitamin k from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): 4-amino-2-methyl-1-naphthol, Fat-soluble vitamin, Menadiol acetate, Menadiol sodium phosphate, Menadione sodium bisulfite, Menaquinone, Menatetrenone, Methylphytyl naphthoquinone, Phylloquinone, Phytomenadione, Vitamin k.

On Jun, 04, 2026

7,499 people reported to have side effects when taking drugs with ingredients of vitamin k.
Among them, 27 people (0.36%) have Mouth ulcers

What is Mouth ulcers?

Mouth ulcers is found to be associated with 1,342 drugs and 2,171 conditions by eHealthMe. Check the latest studies of Mouth ulcers.

Number of reports submitted per year:

Could drugs with ingredients of vitamin k cause Mouth ulcers?

Time on drugs with ingredients of vitamin k when people have Mouth ulcers *:

  • < 1 month: 66.67 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 33.33 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Mouth ulcers when taking drugs with ingredients of vitamin k *:

  • female: 77.27 %
  • male: 22.73 %

Age of people who have Mouth ulcers when taking drugs with ingredients of vitamin k *:

  • 0-1: 0.0 %
  • 2-9: 4.76 %
  • 10-19: 4.76 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 9.52 %
  • 60+: 80.95 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 14.81%
  2. Vitamin B Complex Deficiency: 2 people, 7.41%
  3. Multiple Myeloma (cancer of the plasma cells): 2 people, 7.41%
  4. Thrombocytopenia (decrease of platelets in blood): 2 people, 7.41%
  5. Nausea (feeling of having an urge to vomit): 2 people, 7.41%
  6. Bleeding Disorders: 1 person, 3.70%
  7. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 3.70%
  8. Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 1 person, 3.70%
  9. Gastrointestinal Hypermotility (over activity of the intestinal tract): 1 person, 3.70%
  10. Hypoproteinaemia (too little prolactin circulating in the blood): 1 person, 3.70%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Vitamin B12: 15 people, 55.56%
  2. Humira: 15 people, 55.56%
  3. Enbrel: 15 people, 55.56%
  4. Vitamin D3: 14 people, 51.85%
  5. Plaquenil: 14 people, 51.85%
  6. Leflunomide: 8 people, 29.63%
  7. Sulfasalazine: 8 people, 29.63%
  8. Methotrexate: 8 people, 29.63%
  9. Naproxen: 8 people, 29.63%
  10. Venlafaxine Hydrochloride: 5 people, 18.52%

Other side effects people have besides Mouth ulcers *:

You may use this to check any potential undetected side effects.

  1. Joint Pain: 20 people, 74.07%
  2. Hair Loss: 19 people, 70.37%
  3. Rashes (redness): 16 people, 59.26%
  4. Epicondylitis (tennis elbow): 15 people, 55.56%
  5. Feeling Abnormal: 15 people, 55.56%
  6. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 15 people, 55.56%
  7. Joint Swelling: 15 people, 55.56%
  8. Nausea And Vomiting: 6 people, 22.22%
  9. Diarrhea: 6 people, 22.22%
  10. Headache (pain in head): 5 people, 18.52%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

How the study uses the data?

The study uses data from the FDA. It is based on vitamin k. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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