Donepezil and Loss of consciousness for Men aged 50-59 (a phase IV clinical study of FDA data)

Summary:

Loss of consciousness is found for men aged 50-59 who take Donepezil (donepezil hydrochloride). This study is created by eHealthMe based on reports of 313 men aged 50-59 from the FDA, and is updated regularly. The information that eHealthMe analyzes includes:

Time on Donepezil when people have Loss of consciousness
Top conditions
Top co-used drugs
Top other side effects

On Aug, 12, 2026

313 men aged 50-59 reported to have side effects when taking Donepezil.
Among them, 2 people (0.64%) have Loss of consciousness

What is Donepezil?

Donepezil has active ingredients of donepezil hydrochloride. It is often used in dementia. eHealthMe is studying from 24,564 Donepezil users. Check the latest studies of Donepezil.

What is Loss of consciousness?

Loss of consciousness is found to be associated with 2,546 drugs and 3,071 conditions by eHealthMe. Check the latest studies of Loss of consciousness.

Number of reports submitted per year:

Could Donepezil cause Loss of consciousness in men aged 50-59?

Severity of Loss of consciousness

n/a

How people recovered from Loss of consciousness

n/a

Top conditions involved for these people *:

You may use this to check any potential undetected conditions.

Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 50.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 50.00%
High Blood Pressure: 1 person, 50.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 50.00%
Fatigue (feeling of tiredness): 1 person, 50.00%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 1 person, 50.00%
Cardiac Failure: 1 person, 50.00%
Bleeding Disorders: 1 person, 50.00%

Top co-used drugs for these people *:

You may use this to check any potential interacting drugs.

Warfarin Sodium: 1 person, 50.00%
Omeprazole: 1 person, 50.00%
Nebivolol Hydrochloride: 1 person, 50.00%
Modafinil: 1 person, 50.00%
Gilenya: 1 person, 50.00%
Entresto: 1 person, 50.00%
Crestor: 1 person, 50.00%
Citicoline: 1 person, 50.00%
Aspirin: 1 person, 50.00%

Top other side effects for these people *:

You may use this to check any potential undetected side effects.

Fatigue (feeling of tiredness): 2 people, 100.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 50.00%
Speech Disorder: 1 person, 50.00%
Blood Urea Increased: 1 person, 50.00%
Consciousness - Decreased: 1 person, 50.00%
Dizziness: 1 person, 50.00%
Ejection Fraction Decreased (systolic heart failure): 1 person, 50.00%
Exercise Tolerance Decreased: 1 person, 50.00%
Fainting (loss of consciousness and postural tone): 1 person, 50.00%
Gait Disturbance: 1 person, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Donepezil and have Loss of consciousness?

- Check whether Loss of consciousness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies:

Donepezil and Loss of consciousness

How the study uses the data?

The study is based on (applicable) gender, age, donepezil hydrochloride (the active ingredients of Donepezil) and Donepezil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.