Duragesic and Fatigue for Men aged 40-49 (a phase IV clinical study of FDA data)

Summary:

Fatigue is found for men aged 40-49 who take Duragesic (fentanyl). This study is created by eHealthMe based on reports of 1,945 men aged 40-49 from the FDA, and is updated regularly. The information that eHealthMe analyzes includes:

Time on Duragesic when people have Fatigue
Top conditions
Top co-used drugs
Top other side effects

On Jun, 17, 2026

1,945 men aged 40-49 reported to have side effects when taking Duragesic.
Among them, 121 people (6.22%) have Fatigue

What is Duragesic?

Duragesic has active ingredients of fentanyl. eHealthMe is studying from 66,597 Duragesic users. Check the latest studies of Duragesic.

What is Fatigue?

Fatigue (feeling of tiredness) is found to be associated with 4,026 drugs and 6,378 conditions by eHealthMe. Check the latest studies of Fatigue.

Number of reports submitted per year:

Could Duragesic cause Fatigue in men aged 40-49?

Time on Duragesic when people have Fatigue *

Severity of Fatigue

n/a

How people recovered from Fatigue

n/a

Top conditions involved for these people *:

You may use this to check any potential undetected conditions.

Pain: 29 people, 23.97%
Bone Pain: 10 people, 8.26%
Back Pain: 9 people, 7.44%
Prostate Cancer: 6 people, 4.96%
Metastases To Bone (cancer spreads to bone): 5 people, 4.13%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 4.13%
Joint Pain: 4 people, 3.31%
Insomnia (sleeplessness): 3 people, 2.48%
Migraine (headache): 3 people, 2.48%
Nausea (feeling of having an urge to vomit): 3 people, 2.48%

Top co-used drugs for these people *:

You may use this to check any potential interacting drugs.

Top other side effects for these people *:

You may use this to check any potential undetected side effects.

Stress And Anxiety: 55 people, 45.45%
Constipation: 45 people, 37.19%
Insomnia (sleeplessness): 45 people, 37.19%
Nausea (feeling of having an urge to vomit): 45 people, 37.19%
Back Pain: 44 people, 36.36%
Dyspnea (difficult or laboured breathing): 44 people, 36.36%
Weakness: 43 people, 35.54%
Depression: 42 people, 34.71%
Pain: 40 people, 33.06%
Weight Decreased: 36 people, 29.75%

* Approximation only. Some reports may have incomplete information.

Do you take Duragesic and have Fatigue?

- Check whether Fatigue is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related publications that referenced our studies:

Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .

Related studies:

Duragesic and Fatigue

How the study uses the data?

The study is based on (applicable) gender, age, fentanyl (the active ingredients of Duragesic) and Duragesic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.